Ursodeoxycholic acid is a bile acid used primarily in the treatment of gallstones and primary biliary cholangitis, an autoimmune liver disease. It works by reducing cholesterol levels in bile, thus aiding in the dissolution of cholesterol gallstones and improving liver function. Additionally, it is indicated for treating liver diseases in children and is beneficial in managing conditions related to cystic fibrosis. Its clinical significance lies in its ability to enhance bile flow and protect liver cells from damage. In summary, ursodeoxycholic acid is essential for promoting liver health and managing cholesterol-related disorders.
Ursodeoxycholic acid reduces cholesterol absorption in the intestine and promotes the dissolution of cholesterol gallstones by decreasing hepatic cholesterol secretion and increasing bile salt concentration.























