I-Brom Plus Ophthalmic Solution
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Bromfenac (0.09% w/v) + Moxifloxacin (0.5% w/v)
Packet of 5 ml • Liquid
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Active composition
+1 more active ingredient
Bromfenac inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins involved in inflammation.
Moxifloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Medical applications
I-Brom Plus Ophthalmic Solution is a combination medication containing Bromfenac 0.09% w/v, a nonsteroidal anti-inflammatory drug (NSAID), and Moxifloxacin 0.5% w/v, a broad-spectrum fluoroquinolone antibiotic. This formulation is indicated for the treatment and prevention of ocular inflammation and bacterial infections, particularly following cataract surgery or other ophthalmic procedures.
Bromfenac exerts its effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and edema. Moxifloxacin acts by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, leading to bactericidal activity against a wide range of Gram-positive and Gram-negative pathogens.
The combined use of Bromfenac and Moxifloxacin in I-Brom Plus Ophthalmic Solution provides both anti-inflammatory and antimicrobial effects, facilitating improved patient outcomes by minimizing postoperative inflammation and preventing secondary infections. The solution is typically administered as eye drops, with dosing frequency and duration determined by the prescribing ophthalmologist based on the severity of the condition.
Patients should be advised to avoid contamination of the dropper tip and adhere strictly to the prescribed regimen to ensure efficacy and reduce the risk of resistance or adverse effects.
How to use I-Brom Plus Ophthalmic Solution This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
No interaction found/established
High Risk
Information regarding the use of I-Brom Plus Ophthalmic Solution during pregnancy is not available. Please consult your doctor.
Medical Advice
I-Brom Plus Ophthalmic Solution may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Exercise Caution
No interaction found/established
Regular Checkup
Information regarding the use of I-Brom Plus Ophthalmic Solution during breastfeeding is not available. Please consult your doctor.
Consult Doctor
No interaction found/established
Regular Checkup
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