Ogain Prefilled Syringe
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Packet of 1 ml • LiquidPrescription requiredSchedule H
Ogain Prefilled Syringe
Denosumab (60mg)
₹19687.50
Packet of 1 ml • Liquid
A valid prescription is required for this medicine.
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Active composition
Denosumab 60 mg
How It Works
Denosumab binds to RANK ligand, inhibiting osteoclast formation and activity, thereby decreasing bone resorption.
Medicine Strength
60 mg
Uses & Benefits
Medical applications
Ogain Prefilled Syringe contains Denosumab 60 mg, a fully human monoclonal antibody that specifically targets and inhibits RANKL (Receptor Activator of Nuclear Factor Kappa-B Ligand), a key mediator of osteoclast formation, function, and survival. By binding to RANKL, Denosumab reduces bone resorption and increases bone mass and strength in both cortical and trabecular bone. Ogain is indicated for the treatment of osteoporosis in postmenopausal women and men at increased risk of fractures, as well as for the prevention of skeletal-related events in patients with bone metastases from solid tumors.
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The prefilled syringe formulation allows for subcutaneous administration, typically every six months, providing a convenient dosing regimen that enhances patient compliance. Clinical studies have demonstrated that Denosumab significantly reduces the incidence of vertebral, non-vertebral, and hip fractures. Additionally, it is used in the management of giant cell tumor of bone and other conditions characterized by increased bone turnover.
Patients receiving Ogain should be monitored for hypocalcemia, and adequate intake of calcium and vitamin D is recommended to minimize this risk. Contraindications include hypocalcemia and known hypersensitivity to Denosumab or any of the excipients. Regular dental examinations are advised due to the potential risk of osteonecrosis of the jaw.
Dosage & How to Use
How to use Ogain Prefilled Syringe Your doctor or nurse will use this device to give medicine. You or your care giver may be taught on how to use this device at home.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Ogain Prefilled Syringe. Please consult your doctor.
High Risk
Pregnancy
Ogain Prefilled Syringe is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Driving
Ogain Prefilled Syringe does not usually affect your ability to drive.
Exercise Caution
Liver
Ogain Prefilled Syringe should be used with caution in patients with severe liver disease. Dose adjustment of Ogain Prefilled Syringe may be needed. Please consult your doctor.
Regular Checkup
Breastfeeding
Ogain Prefilled Syringe is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Ogain Prefilled Syringe should be used with caution in patients with severe kidney disease. Dose adjustment of Ogain Prefilled Syringe may be needed. Please consult your doctor.
Regular Checkup
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