Lupin Tofakin Tablet ER
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1 units • OtherPrescription requiredSchedule H
Lupin Tofakin Tablet ER
Tofacitinib (11mg)
₹566.90
1 units • Other
A valid prescription is required for this medicine.
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Active composition
Tofacitinib 11 mg
How It Works
Tofacitinib inhibits Janus kinases, disrupting signaling pathways involved in inflammation and immune responses.
Medicine Strength
11 mg
Uses & Benefits
Medical applications
Rheumatoid ArthritisHeadacheInfectionUlcer
Lupin Tofakin Tablet ER contains Tofacitinib 11 mg, an extended-release formulation of a Janus kinase (JAK) inhibitor indicated for the treatment of moderate to severe rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in adult patients who have had an inadequate response or intolerance to conventional therapies. Tofacitinib exerts its therapeutic effect by selectively inhibiting JAK enzymes, thereby modulating the signaling pathways involved in the pathogenesis of inflammatory and autoimmune conditions.
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The extended-release formulation allows for once-daily dosing, improving patient adherence and maintaining consistent plasma drug concentrations. Clinical studies have demonstrated that Tofacitinib effectively reduces signs and symptoms, inhibits structural joint damage, and improves physical function in rheumatoid arthritis patients. It also helps achieve and maintain clinical remission in ulcerative colitis and reduces the symptoms of psoriatic arthritis.
Common adverse effects include upper respiratory tract infections, headache, and gastrointestinal disturbances. Serious risks involve infections, malignancies, and thrombosis; therefore, patients require regular monitoring, including complete blood counts, liver function tests, and lipid profiles. Lupin Tofakin Tablet ER should be prescribed and administered under specialist supervision, with careful consideration of contraindications such as active infections and hypersensitivity to the active ingredient.
Dosage & How to Use
Pyrrolo Pyrimidine Derivative
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Lupin Tofakin Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Lupin Tofakin Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
Lupin Tofakin Tablet ER should be used with caution in patients with severe kidney disease. Dose adjustment of Lupin Tofakin Tablet ER may be needed. Please consult your doctor.
Exercise Caution
Breastfeeding
Lupin Tofakin Tablet ER does not usually affect your ability to drive.
Consult Doctor
Kidney
Lupin Tofakin Tablet ER should be used with caution in patients with severe liver disease. Dose adjustment of Lupin Tofakin Tablet ER may be needed. Please consult your doctor.
Regular Checkup
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