Hepcvel Tablet
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Bottle of 28 tablets • TabletPrescription requiredSchedule H
Hepcvel Tablet
Sofosbuvir (400mg) + Velpatasvir (100mg)
₹16406.00
Bottle of 28 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Sofosbuvir 400 mg
+1 more active ingredient
How It Works
Sofosbuvir inhibits the HCV NS5B polymerase, preventing viral replication.
Medicine Strength
400 mg
All Active Ingredients
Sofosbuvir400 mg
Velpatasvir100 mg
Uses & Benefits
Medical applications
InfectionViral
Hepcvel Tablet contains a fixed-dose combination of Sofosbuvir 400 mg and Velpatasvir 100 mg, indicated for the treatment of chronic hepatitis C virus (HCV) infection across all major genotypes (1-6) in adult patients. Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor that prevents viral RNA replication, while Velpatasvir is an NS5A inhibitor that disrupts viral replication and assembly.
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The combination offers a potent, once-daily oral regimen that has demonstrated high sustained virologic response (SVR) rates, effectively achieving viral clearance with a favorable safety profile. Hepcvel is typically administered for 12 weeks, with or without ribavirin, depending on the patient’s HCV genotype, prior treatment history, and presence of cirrhosis. It is contraindicated in patients with known hypersensitivity to any component of the formulation.
Caution is advised when co-administered with drugs that induce or inhibit P-glycoprotein or CYP enzymes, as these may affect plasma concentrations of Sofosbuvir and Velpatasvir. Hepcvel is not recommended for use in patients with severe hepatic impairment (Child-Pugh C) or end-stage renal disease without close monitoring. Regular monitoring of liver function tests and HCV RNA levels is essential to assess therapeutic response and detect potential adverse effects.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Information regarding the use of Hepcvel Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Pregnancy
Hepcvel Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
Driving
Hepcvel Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Hepcvel Tablet may be needed. Please consult your doctor. Limited information is available on the use of Hepcvel Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Exercise Caution
Breastfeeding
Hepcvel Tablet may cause side effects which could affect your ability to drive. Hepcvel Tablet, when taken together with other medicines for the treatment of hepatitis c infection, may produce dizziness, blurred vision and this may affect your ability to drive.
Consult Doctor
Kidney
Hepcvel Tablet is safe to use in patients with liver disease. No dose adjustment of Hepcvel Tablet is recommended. However, inform your doctor if you have any kidney disease as regular monitoring of liver function tests may be advised in some patients while taking this medicine.
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