
Lidocaine (1.5% w/w) + Nifedipine (0.3% w/w)
Active composition
+1 more active ingredient
Lidocaine blocks sodium channels in nerve membranes, preventing the initiation and conduction of nerve impulses.
Nifedipine inhibits L-type calcium channels in vascular smooth muscle, leading to vasodilation and reduced blood pressure.
Medical applications
Escot Cream is a topical formulation containing Lidocaine 1.5% w/w and Nifedipine 0.3% w/w, designed for the management of localized pain and vascular conditions. Lidocaine, a potent local anesthetic, acts by blocking sodium channels in neuronal membranes, thereby inhibiting nerve impulse conduction and providing effective analgesia. Nifedipine, a calcium channel blocker, promotes vasodilation by relaxing vascular smooth muscle, which enhances blood flow and reduces ischemic discomfort. The combination of these active ingredients in Escot Cream offers dual therapeutic benefits, making it suitable for conditions such as anal fissures, peripheral vascular disorders, and other localized pain syndromes associated with vascular spasm or ischemia. The cream is applied topically to the affected area, allowing for targeted delivery with minimal systemic absorption, thereby reducing the risk of systemic side effects. Escot Cream should be used as directed by a healthcare professional, with caution advised in patients with known hypersensitivity to either component. It is contraindicated in individuals with severe hypotension or certain cardiac conditions due to the vasodilatory effects of nifedipine. Overall, Escot Cream provides an effective, localized treatment option for pain relief and vascular relaxation in relevant clinical scenarios.
How to use Escot Rectal Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Escot Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
Escot Cream should be used with caution in patients with liver disease. Dose adjustment of Escot Cream may be needed. Please consult your doctor.
Regular Checkup
Escot Cream is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Escot Cream should be used with caution in patients with severe kidney disease. Dose adjustment of Escot Cream may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Escot Cream

Lidocaine (1.5% w/w) + Nifedipine (0.3% w/w)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Lidocaine blocks sodium channels in nerve membranes, preventing the initiation and conduction of nerve impulses.
Nifedipine inhibits L-type calcium channels in vascular smooth muscle, leading to vasodilation and reduced blood pressure.
Medical applications
Escot Cream is a topical formulation containing Lidocaine 1.5% w/w and Nifedipine 0.3% w/w, designed for the management of localized pain and vascular conditions. Lidocaine, a potent local anesthetic, acts by blocking sodium channels in neuronal membranes, thereby inhibiting nerve impulse conduction and providing effective analgesia. Nifedipine, a calcium channel blocker, promotes vasodilation by relaxing vascular smooth muscle, which enhances blood flow and reduces ischemic discomfort. The combination of these active ingredients in Escot Cream offers dual therapeutic benefits, making it suitable for conditions such as anal fissures, peripheral vascular disorders, and other localized pain syndromes associated with vascular spasm or ischemia. The cream is applied topically to the affected area, allowing for targeted delivery with minimal systemic absorption, thereby reducing the risk of systemic side effects. Escot Cream should be used as directed by a healthcare professional, with caution advised in patients with known hypersensitivity to either component. It is contraindicated in individuals with severe hypotension or certain cardiac conditions due to the vasodilatory effects of nifedipine. Overall, Escot Cream provides an effective, localized treatment option for pain relief and vascular relaxation in relevant clinical scenarios.
How to use Escot Rectal Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Escot Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
Escot Cream should be used with caution in patients with liver disease. Dose adjustment of Escot Cream may be needed. Please consult your doctor.
Regular Checkup
Escot Cream is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Escot Cream should be used with caution in patients with severe kidney disease. Dose adjustment of Escot Cream may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Escot Cream















