Rifaximin is an antibiotic used to treat traveler's diarrhea, hepatic encephalopathy, and irritable bowel syndrome with diarrhea (IBS-D). It works by inhibiting bacterial RNA synthesis, thereby reducing the bacterial load in the gut. Rifaximin is effective against a broad spectrum of bacteria. Common side effects may include headache and nausea, but these usually resolve over time. In summary, Rifaximin is effective in managing gastrointestinal infections and disorders.
Rifaximin binds to the beta-subunit of bacterial RNA polymerase, inhibiting RNA synthesis and leading to bacterial cell death.

















