Entacapone is a medication used in conjunction with levodopa to treat Parkinson's disease symptoms. It enhances the effectiveness of levodopa by inhibiting catechol-O-methyltransferase (COMT), an enzyme that breaks down levodopa before it reaches the brain. This leads to increased dopamine availability, improving motor control and reducing symptoms such as tremors and stiffness. In summary, Entacapone is a crucial adjunct therapy for managing Parkinson's disease effectively.
Entacapone inhibits the COMT enzyme, thereby preventing the degradation of levodopa and increasing its bioavailability to the central nervous system.



