Entacom Plus 100 Tablet
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Strip of 10 tablets • TabletPrescription requiredSchedule H
Entacom Plus 100 Tablet
Levodopa (100mg) + Carbidopa (25mg) + Entacapone (200mg)
₹141.56
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Carbidopa 25 mg
+2 more active ingredients
How It Works
Entacapone inhibits the COMT enzyme, thereby preventing the degradation of levodopa and increasing its bioavailability to the central nervous system.
Levodopa is converted to dopamine in the brain, restoring neurotransmitter levels and improving motor function.
Medicine Strength
25 mg
All Active Ingredients
Carbidopa25 mg
Entacapone200 mg
Levodopa100 mg
Uses & Benefits
Medical applications
FluNauseaSkin
Entacom Plus 100 Tablet contains a combination of Levodopa (100mg), Carbidopa (25mg), and Entacapone (200mg), formulated to manage symptoms of Parkinson’s disease. Levodopa serves as a precursor to dopamine, replenishing diminished dopamine levels in the brain, thereby improving motor function. Carbidopa inhibits peripheral decarboxylation of Levodopa, enhancing its central availability and reducing peripheral side effects such as nausea.
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Entacapone, a selective and reversible catechol-O-methyltransferase (COMT) inhibitor, prolongs the half-life of Levodopa by preventing its peripheral metabolism, resulting in more stable and sustained dopaminergic stimulation. This combination is indicated for patients experiencing motor fluctuations and wearing-off phenomena associated with Parkinson’s disease, providing improved symptom control and quality of life.
Entacom Plus 100 is typically administered orally, with dosage individualized based on clinical response and tolerability. Common adverse effects may include dyskinesia, nausea, orthostatic hypotension, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiac, hepatic, or psychiatric disorders. Regular monitoring by a healthcare professional is recommended to optimize therapeutic outcomes and minimize potential side effects.
This combination therapy represents an effective approach to managing advanced Parkinson’s disease symptoms by enhancing and prolonging dopaminergic activity in the central nervous system.
Dosage & How to Use
How to use Entacom Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Entacom Plus 100 Tablet may be taken with or without food, but it is better to take it at a fixed time. Avoid Entacom Plus 100 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is unsafe to consume alcohol with Entacom Plus 100 Tablet.
High Risk
Pregnancy
Entacom Plus 100 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Entacom Plus 100 Tablet may cause side effects which could affect your ability to drive. Caution is advised when driving or operating machinery.
Exercise Caution
Liver
Entacom Plus 100 Tablet should be used with caution in patients with liver disease. Dose adjustment of Entacom Plus 100 Tablet may be needed. Please consult your doctor.
Regular Checkup
Breastfeeding
Entacom Plus 100 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Entacom Plus 100 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Entacom Plus 100 Tablet may be needed. Please consult your doctor.
Regular Checkup
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