
Carbidopa (25mg) + Entacapone (200mg) + Levodopa (100mg)
Active composition
+2 more active ingredients
Entacapone inhibits the COMT enzyme, thereby preventing the degradation of levodopa and increasing its bioavailability to the central nervous system.
Levodopa is converted to dopamine in the brain, restoring neurotransmitter levels and improving motor function.
Medical applications
Entacom Plus 100 Tablet contains a combination of Levodopa (100mg), Carbidopa (25mg), and Entacapone (200mg), formulated to manage symptoms of Parkinson’s disease. Levodopa serves as a precursor to dopamine, replenishing diminished dopamine levels in the brain, thereby improving motor function. Carbidopa inhibits peripheral decarboxylation of Levodopa, enhancing its central availability and reducing peripheral side effects such as nausea. Entacapone, a selective and reversible catechol-O-methyltransferase (COMT) inhibitor, prolongs the half-life of Levodopa by preventing its peripheral metabolism, resulting in more stable and sustained dopaminergic stimulation. This combination is indicated for patients experiencing motor fluctuations and wearing-off phenomena associated with Parkinson’s disease, providing improved symptom control and quality of life. Entacom Plus 100 is typically administered orally, with dosage individualized based on clinical response and tolerability. Common adverse effects may include dyskinesia, nausea, orthostatic hypotension, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiac, hepatic, or psychiatric disorders. Regular monitoring by a healthcare professional is recommended to optimize therapeutic outcomes and minimize potential side effects. This combination therapy represents an effective approach to managing advanced Parkinson’s disease symptoms by enhancing and prolonging dopaminergic activity in the central nervous system.
How to use Entacom Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Entacom Plus 100 Tablet may be taken with or without food, but it is better to take it at a fixed time. Avoid Entacom Plus 100 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Entacom Plus 100 Tablet.
High Risk
Entacom Plus 100 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Entacom Plus 100 Tablet may cause side effects which could affect your ability to drive. Caution is advised when driving or operating machinery.
Exercise Caution
Entacom Plus 100 Tablet should be used with caution in patients with liver disease. Dose adjustment of Entacom Plus 100 Tablet may be needed. Please consult your doctor.
Regular Checkup
Entacom Plus 100 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Entacom Plus 100 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Entacom Plus 100 Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Entacom Plus 100 Tablet

Levodopa (100mg) + Carbidopa (25mg) + Entacapone (200mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+2 more active ingredients
Entacapone inhibits the COMT enzyme, thereby preventing the degradation of levodopa and increasing its bioavailability to the central nervous system.
Levodopa is converted to dopamine in the brain, restoring neurotransmitter levels and improving motor function.
Medical applications
Entacom Plus 100 Tablet contains a combination of Levodopa (100mg), Carbidopa (25mg), and Entacapone (200mg), formulated to manage symptoms of Parkinson’s disease. Levodopa serves as a precursor to dopamine, replenishing diminished dopamine levels in the brain, thereby improving motor function. Carbidopa inhibits peripheral decarboxylation of Levodopa, enhancing its central availability and reducing peripheral side effects such as nausea. Entacapone, a selective and reversible catechol-O-methyltransferase (COMT) inhibitor, prolongs the half-life of Levodopa by preventing its peripheral metabolism, resulting in more stable and sustained dopaminergic stimulation. This combination is indicated for patients experiencing motor fluctuations and wearing-off phenomena associated with Parkinson’s disease, providing improved symptom control and quality of life. Entacom Plus 100 is typically administered orally, with dosage individualized based on clinical response and tolerability. Common adverse effects may include dyskinesia, nausea, orthostatic hypotension, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiac, hepatic, or psychiatric disorders. Regular monitoring by a healthcare professional is recommended to optimize therapeutic outcomes and minimize potential side effects. This combination therapy represents an effective approach to managing advanced Parkinson’s disease symptoms by enhancing and prolonging dopaminergic activity in the central nervous system.
How to use Entacom Plus Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Entacom Plus 100 Tablet may be taken with or without food, but it is better to take it at a fixed time. Avoid Entacom Plus 100 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Entacom Plus 100 Tablet.
High Risk
Entacom Plus 100 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Entacom Plus 100 Tablet may cause side effects which could affect your ability to drive. Caution is advised when driving or operating machinery.
Exercise Caution
Entacom Plus 100 Tablet should be used with caution in patients with liver disease. Dose adjustment of Entacom Plus 100 Tablet may be needed. Please consult your doctor.
Regular Checkup
Entacom Plus 100 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Entacom Plus 100 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Entacom Plus 100 Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Entacom Plus 100 Tablet















