Olmin 40-H Tablet
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Hydrochlorothiazide (12.5mg) + Olmesartan Medoxomil (40mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Olmesartan Medoxomil blocks angiotensin II receptors, preventing vasoconstriction and lowering blood pressure.
Medical applications
Olmin 40-H Tablet is a combination antihypertensive medication containing Hydrochlorothiazide 12.5 mg and Olmesartan Medoxomil 40 mg. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, thereby reducing blood volume and lowering blood pressure. Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, leading to vasodilation and decreased aldosterone secretion, which further contributes to blood pressure reduction.
The combination of these two agents provides complementary mechanisms to effectively manage hypertension, improving blood pressure control in patients who require more than one agent. Olmin 40-H is indicated for the treatment of essential hypertension and may reduce the risk of cardiovascular events such as stroke and myocardial infarction. It is generally well tolerated; however, monitoring of electrolytes, renal function, and blood pressure is recommended during therapy.
Contraindications include hypersensitivity to any component, severe renal impairment, and pregnancy. Patients should be advised to maintain adequate hydration and report any adverse effects such as dizziness, hypotension, or electrolyte imbalances to their healthcare provider promptly.
How to use Olmin H Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olmin 40-H Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Olmin 40-H Tablet may cause excessive drowsiness with alcohol.
High Risk
Olmin 40-H Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Olmin 40-H Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Olmin 40-H Tablet should be used with caution in patients with liver disease. Dose adjustment of Olmin 40-H Tablet may be needed. Please consult your doctor.
Regular Checkup
Olmin 40-H Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
Olmin 40-H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Olmin 40-H Tablet may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment.
Regular Checkup
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