Olmibite AM 40 Tablet
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Olmesartan Medoxomil (40mg) + Amlodipine (5mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Olmesartan Medoxomil blocks angiotensin II receptors, preventing vasoconstriction and lowering blood pressure.
Amlodipine inhibits calcium ion influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced myocardial oxygen demand.
Medical applications
Olmibite AM 40 Tablet is a combination antihypertensive medication containing Olmesartan Medoxomil 40 mg and Amlodipine 5 mg. Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, thereby preventing vasoconstriction and aldosterone secretion, leading to vasodilation and reduced blood pressure.
Amlodipine, a dihydropyridine calcium channel blocker, inhibits calcium ion influx into vascular smooth muscle and cardiac muscle, promoting arterial vasodilation and decreasing peripheral vascular resistance. The synergistic action of these two agents provides effective blood pressure control in patients with essential hypertension, especially those inadequately managed with monotherapy.
Olmibite AM 40 is indicated for the treatment of hypertension to reduce the risk of cardiovascular events such as stroke and myocardial infarction. It is generally well tolerated; however, adverse effects may include dizziness, headache, peripheral edema, and fatigue. Caution is advised in patients with hepatic impairment, severe hypotension, or a history of angioedema. Regular monitoring of blood pressure, renal function, and electrolytes is recommended during therapy.
Olmibite AM 40 Tablet should be administered as prescribed by a healthcare professional to achieve optimal therapeutic outcomes.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Olmibite AM 40 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Olmibite AM 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Olmibite AM 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Olmibite AM 40 Tablet may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment.
Exercise Caution
Olmibite AM 40 Tablet may cause side effects which could affect your ability to drive. Olmibite AM 40 Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.
Consult Doctor
Olmibite AM 40 Tablet should be used with caution in patients with liver disease. Dose adjustment of Olmibite AM 40 Tablet may be needed. Please consult your doctor. Olmibite AM 40 Tablet is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.
Regular Checkup
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