Olmat-H Tablet is a combination antihypertensive medication containing Hydrochlorothiazide 12.5 mg and Olmesartan Medoxomil 20 mg. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, thereby reducing blood volume and lowering blood pressure. Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, leading to vasodilation and decreased aldosterone secretion, which further contributes to blood pressure reduction. The combination of these two agents provides a complementary mechanism of action, enhancing antihypertensive efficacy while minimizing adverse effects associated with higher doses of individual components. Olmat-H is indicated for the treatment of hypertension to reduce the risk of cardiovascular events such as stroke and myocardial infarction. It is generally well tolerated; however, monitoring of electrolytes, renal function, and blood pressure is recommended during therapy. Contraindications include hypersensitivity to components, severe renal impairment, and pregnancy. Patients should adhere to prescribed dosages and consult healthcare providers before initiating or discontinuing therapy.

Dosage & How to Use