Olmat 40 H Tablet
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Hydrochlorothiazide (12.5mg) + Olmesartan Medoxomil (40mg)
Strip of 15 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Olmesartan Medoxomil blocks angiotensin II receptors, preventing vasoconstriction and lowering blood pressure.
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Medical applications
Olmat 40 H Tablet is a combination antihypertensive medication containing Olmesartan Medoxomil 40 mg and Hydrochlorothiazide 12.5 mg. Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, thereby preventing vasoconstriction and aldosterone secretion, leading to vasodilation and reduction in blood pressure.
Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, contributing to decreased blood volume and peripheral resistance. The combination of these two agents provides complementary mechanisms to achieve effective blood pressure control in patients with essential hypertension, especially those who do not respond adequately to monotherapy.
Olmat 40 H is indicated for the treatment of hypertension to reduce the risk of cardiovascular events such as stroke and myocardial infarction. It is important to monitor electrolytes, renal function, and blood pressure regularly during therapy. Caution is advised in patients with renal or hepatic impairment, and it is contraindicated in pregnancy and patients with hypersensitivity to any component.
Adverse effects may include dizziness, hypotension, electrolyte imbalance, and gastrointestinal disturbances. Patient adherence and lifestyle modifications are essential for optimal therapeutic outcomes.
How to use Olmat-H Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olmat 40 H Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Olmat 40 H Tablet may cause excessive drowsiness with alcohol.
High Risk
Olmat 40 H Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Olmat 40 H Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Olmat 40 H Tablet should be used with caution in patients with liver disease. Dose adjustment of Olmat 40 H Tablet may be needed. Please consult your doctor.
Regular Checkup
Olmat 40 H Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
Olmat 40 H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Olmat 40 H Tablet may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment.
Regular Checkup
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