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  4. Nucala Injection
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Nucala Injection

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Pre of 1 injection • OtherPrescription requiredSchedule H

Nucala Injection

Mepolizumab (100mg)

Glaxo SmithKline Pharmaceuticals LtdAsthma
₹79852.00

Pre of 1 injection • Other

A valid prescription is required for this medicine.

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Active composition

Mepolizumab 100 mg

How It Works

Mepolizumab binds to IL-5, preventing it from interacting with its receptor on eosinophils, thereby reducing eosinophil levels and associated inflammation.

Medicine Strength
100 mg

Uses & Benefits

Medical applications

PainInflammationHeadacheInfection

Nucala Injection contains mepolizumab 100 mg, a humanized monoclonal antibody targeting interleukin-5 (IL-5), indicated for the treatment of severe eosinophilic asthma and other eosinophil-driven diseases. By selectively binding to IL-5, mepolizumab inhibits the activation and survival of eosinophils, reducing airway inflammation and improving clinical outcomes. Nucala is administered via subcutaneous injection, typically once every four weeks, under the supervision of a healthcare professional.

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Clinical studies have demonstrated its efficacy in decreasing the frequency of asthma exacerbations, improving lung function, and reducing the need for oral corticosteroids in patients with severe eosinophilic asthma inadequately controlled by standard therapies. Additionally, Nucala is approved for use in eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES).

Common adverse reactions include headache, injection site reactions, back pain, and fatigue. Hypersensitivity reactions, including anaphylaxis, though rare, may occur and require immediate medical attention. Prior to initiation, patients should be evaluated for parasitic infections, as eosinophils play a role in host defense. Nucala should be used with caution in patients with active infections.

Regular monitoring of clinical response and eosinophil counts is recommended to assess treatment efficacy and safety.

Nucala Injection packaging
Medicine details

Nucala Injection

Composition

1 ingredient
  • Mepolizumab100 mg
Dosage & how to useRead the usage informationSafety & side effectsReview precautions

Dosage & How to Use

Interleukin-5 Antagonist

Safety Advice

Important precautions

Side effects

Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.

Safety Advice

Alcohol

Nucala Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

High Risk

Pregnancy

Nucala Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Medical Advice

Driving

There is limited information available on the use of Nucala Injection in patients with kidney disease. Please consult your doctor.

Exercise Caution

Breastfeeding

Nucala Injection does not usually affect your ability to drive.

Consult Doctor

Kidney

Nucala Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nucala Injection may not be needed in these patients. Please consult your doctor.

Regular Checkup

Customer Reviews

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