Nucala 100mg Injection
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Vial of 1 injection • InjectionPrescription requiredSchedule H
Nucala 100mg Injection
Mepolizumab (100mg)
₹79853.00
Vial of 1 injection • Injection
A valid prescription is required for this medicine.
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Active composition
Mepolizumab 100 mg
How It Works
Mepolizumab binds to IL-5, preventing it from interacting with its receptor on eosinophils, thereby reducing eosinophil levels and associated inflammation.
Medicine Strength
100 mg
Uses & Benefits
Medical applications
PainInflammationHeadacheInfection
Nucala 100mg Injection contains mepolizumab, a humanized monoclonal antibody targeting interleukin-5 (IL-5), indicated for the treatment of severe eosinophilic asthma. By selectively binding to IL-5, mepolizumab inhibits the growth, differentiation, recruitment, activation, and survival of eosinophils, thereby reducing airway inflammation and exacerbations associated with eosinophilic asthma.
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Nucala is administered via subcutaneous injection at a dose of 100 mg every four weeks. It is approved as an add-on maintenance treatment for patients aged 6 years and older with severe eosinophilic asthma inadequately controlled despite high-dose inhaled corticosteroids and additional asthma controllers. Clinical trials have demonstrated that Nucala significantly reduces the frequency of asthma exacerbations, improves lung function, and enhances quality of life.
Additionally, Nucala is indicated for eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES) in adults, where it helps control eosinophil-driven inflammation. Common adverse effects include headache, injection site reactions, and back pain. Prior to initiation, patients should be evaluated for parasitic infections, as eosinophils play a role in host defense.
Nucala should be administered under the supervision of a healthcare professional experienced in managing severe asthma or eosinophilic disorders.
Dosage & How to Use
Interleukin-5 Antagonist
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Nucala 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
Nucala 100mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Medical Advice
Driving
There is limited information available on the use of Nucala 100mg Injection in patients with kidney disease. Please consult your doctor.
Exercise Caution
Breastfeeding
Nucala 100mg Injection does not usually affect your ability to drive.
Consult Doctor
Kidney
Nucala 100mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nucala 100mg Injection may not be needed in these patients. Please consult your doctor.
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