
Cilnidipine (10mg) + Telmisartan (40mg) + Metoprolol Succinate (50mg)
Active composition
+2 more active ingredients
Cilnidipine inhibits L-type and N-type calcium channels in vascular smooth muscle, leading to vasodilation and reduced blood pressure.
Telmisartan selectively blocks angiotensin II receptors, leading to vasodilation and decreased blood pressure.
Metoprolol Succinate blocks beta-1 adrenergic receptors, leading to decreased heart rate and contractility, thereby lowering blood pressure.
Medical applications
Met XL Trio 50 Tablet ER is a combination antihypertensive medication containing Cilnidipine (10 mg), Metoprolol Succinate (50 mg), and Telmisartan (40 mg). This extended-release formulation is designed to provide sustained blood pressure control in patients with hypertension. Cilnidipine, a calcium channel blocker, acts by inhibiting L-type and N-type calcium channels, resulting in vasodilation and reduced peripheral resistance. Metoprolol Succinate, a selective beta-1 adrenergic receptor blocker, decreases heart rate and myocardial contractility, thereby reducing cardiac output and oxygen demand. Telmisartan, an angiotensin II receptor blocker (ARB), prevents vasoconstriction and aldosterone secretion by selectively blocking the AT1 receptor, contributing to further blood pressure reduction. The combination of these three agents targets multiple physiological pathways involved in hypertension, offering enhanced efficacy compared to monotherapy. Met XL Trio 50 Tablet ER is indicated for the management of essential hypertension, particularly in patients requiring multi-drug therapy to achieve optimal blood pressure control. It should be used under medical supervision, with monitoring for potential side effects such as hypotension, bradycardia, dizziness, and electrolyte imbalances. Dose adjustments may be necessary based on patient response and tolerability.
How to use Met XL Trio Tablet ER Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Met XL Trio 50 Tablet ER is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Met XL Trio 50 Tablet ER.
High Risk
Met XL Trio 50 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Met XL Trio 50 Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Met XL Trio 50 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Met XL Trio 50 Tablet ER may be needed. Please consult your doctor. Use of Met XL Trio 50 Tablet ER is not recommended in patients with severe liver disease.
Regular Checkup
Information regarding the use of Met XL Trio 50 Tablet ER during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Met XL Trio 50 Tablet ER in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Met XL Trio 50 Tablet ER

Cilnidipine (10mg) + Metoprolol Succinate (50mg) + Telmisartan (40mg)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Cilnidipine inhibits L-type and N-type calcium channels in vascular smooth muscle, leading to vasodilation and reduced blood pressure.
Telmisartan selectively blocks angiotensin II receptors, leading to vasodilation and decreased blood pressure.
Metoprolol Succinate blocks beta-1 adrenergic receptors, leading to decreased heart rate and contractility, thereby lowering blood pressure.
Medical applications
Met XL Trio 50 Tablet ER is a combination antihypertensive medication containing Cilnidipine (10 mg), Metoprolol Succinate (50 mg), and Telmisartan (40 mg). This extended-release formulation is designed to provide sustained blood pressure control in patients with hypertension. Cilnidipine, a calcium channel blocker, acts by inhibiting L-type and N-type calcium channels, resulting in vasodilation and reduced peripheral resistance. Metoprolol Succinate, a selective beta-1 adrenergic receptor blocker, decreases heart rate and myocardial contractility, thereby reducing cardiac output and oxygen demand. Telmisartan, an angiotensin II receptor blocker (ARB), prevents vasoconstriction and aldosterone secretion by selectively blocking the AT1 receptor, contributing to further blood pressure reduction. The combination of these three agents targets multiple physiological pathways involved in hypertension, offering enhanced efficacy compared to monotherapy. Met XL Trio 50 Tablet ER is indicated for the management of essential hypertension, particularly in patients requiring multi-drug therapy to achieve optimal blood pressure control. It should be used under medical supervision, with monitoring for potential side effects such as hypotension, bradycardia, dizziness, and electrolyte imbalances. Dose adjustments may be necessary based on patient response and tolerability.
How to use Met XL Trio Tablet ER Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Met XL Trio 50 Tablet ER is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Met XL Trio 50 Tablet ER.
High Risk
Met XL Trio 50 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Met XL Trio 50 Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Met XL Trio 50 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Met XL Trio 50 Tablet ER may be needed. Please consult your doctor. Use of Met XL Trio 50 Tablet ER is not recommended in patients with severe liver disease.
Regular Checkup
Information regarding the use of Met XL Trio 50 Tablet ER during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Met XL Trio 50 Tablet ER in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Met XL Trio 50 Tablet ER















