
Telmisartan (40mg) + Hydrochlorothiazide (12.5mg)
Active composition
+1 more active ingredient
Telmisartan selectively blocks angiotensin II receptors, leading to vasodilation and decreased blood pressure.
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Medical applications
Macsart H Tablet is a combination antihypertensive medication containing Telmisartan 40 mg and Hydrochlorothiazide 12.5 mg. Telmisartan is an angiotensin II receptor blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, thereby reducing vasoconstriction and aldosterone secretion, which leads to decreased blood pressure. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, resulting in reduced plasma volume and peripheral resistance. The combination of these two agents provides complementary mechanisms to effectively control hypertension, especially in patients who require more than one agent to achieve target blood pressure. Macsart H is indicated for the treatment of essential hypertension and may be used when monotherapy with either component is insufficient. The medication should be used with caution in patients with renal or hepatic impairment, electrolyte imbalances, or a history of hypersensitivity to sulfonamides. Common side effects include dizziness, hypotension, electrolyte disturbances, and increased urination. Regular monitoring of blood pressure, renal function, and electrolytes is recommended during therapy. Macsart H Tablet should be taken as prescribed by a healthcare professional to optimize therapeutic outcomes and minimize adverse effects.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Macsart H Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Macsart H Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Macsart H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Macsart H Tablet may be needed. Please consult your doctor. Use of Macsart H Tablet is not recommended in patients with severe kidney disease.
Exercise Caution
Macsart H Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Macsart H Tablet should be used with caution in patients with liver disease. Dose adjustment of Macsart H Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Macsart H Tablet

Telmisartan (40mg) + Hydrochlorothiazide (12.5mg)
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Active composition
+1 more active ingredient
Telmisartan selectively blocks angiotensin II receptors, leading to vasodilation and decreased blood pressure.
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Medical applications
Macsart H Tablet is a combination antihypertensive medication containing Telmisartan 40 mg and Hydrochlorothiazide 12.5 mg. Telmisartan is an angiotensin II receptor blocker (ARB) that selectively inhibits the binding of angiotensin II to the AT1 receptor, thereby reducing vasoconstriction and aldosterone secretion, which leads to decreased blood pressure. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, resulting in reduced plasma volume and peripheral resistance. The combination of these two agents provides complementary mechanisms to effectively control hypertension, especially in patients who require more than one agent to achieve target blood pressure. Macsart H is indicated for the treatment of essential hypertension and may be used when monotherapy with either component is insufficient. The medication should be used with caution in patients with renal or hepatic impairment, electrolyte imbalances, or a history of hypersensitivity to sulfonamides. Common side effects include dizziness, hypotension, electrolyte disturbances, and increased urination. Regular monitoring of blood pressure, renal function, and electrolytes is recommended during therapy. Macsart H Tablet should be taken as prescribed by a healthcare professional to optimize therapeutic outcomes and minimize adverse effects.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Macsart H Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Macsart H Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Macsart H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Macsart H Tablet may be needed. Please consult your doctor. Use of Macsart H Tablet is not recommended in patients with severe kidney disease.
Exercise Caution
Macsart H Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Macsart H Tablet should be used with caution in patients with liver disease. Dose adjustment of Macsart H Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Macsart H Tablet















