
Hydrochlorothiazide (12.5mg) + Irbesartan (150mg)
Active composition
+1 more active ingredient
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Irbesartan selectively blocks angiotensin II receptors, leading to vasodilation and decreased blood pressure.
Medical applications
Irovel H Tablet contains a combination of Irbesartan 150mg and Hydrochlorothiazide 12.5mg, formulated for the management of hypertension. Irbesartan is an angiotensin II receptor antagonist that selectively blocks the binding of angiotensin II to the AT1 receptor, leading to vasodilation and reduced secretion of aldosterone, thereby lowering blood pressure. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, contributing to decreased blood volume and further reduction in blood pressure. The combined action of these agents provides an effective antihypertensive effect, improving blood pressure control in patients inadequately managed with monotherapy. Irovel H is indicated for the treatment of essential hypertension and may reduce the risk of cardiovascular events associated with high blood pressure. It is generally well tolerated; however, monitoring of renal function, electrolytes, and blood pressure is recommended during therapy. Contraindications include hypersensitivity to either component, severe renal impairment, and anuria. Use in pregnancy is not advised due to potential fetal risk. Patients should adhere to prescribed dosages and consult healthcare professionals regarding any adverse effects or drug interactions.
How to use Irovel H Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Irovel H Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Irovel H Tablet may cause excessive drowsiness with alcohol.
High Risk
Irovel H Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Irovel H Tablet should be used with caution in patients with liver disease. Dose adjustment of Irovel H Tablet may be needed. Please consult your doctor.
Regular Checkup
Irovel H Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Irovel H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Irovel H Tablet may be needed. Please consult your doctor. Use of Irovel H Tablet is not recommended in patients with severe kidney disease.
Regular Checkup
0 reviews for Irovel H Tablet

Irbesartan (150mg) + Hydrochlorothiazide (12.5mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Irbesartan selectively blocks angiotensin II receptors, leading to vasodilation and decreased blood pressure.
Medical applications
Irovel H Tablet contains a combination of Irbesartan 150mg and Hydrochlorothiazide 12.5mg, formulated for the management of hypertension. Irbesartan is an angiotensin II receptor antagonist that selectively blocks the binding of angiotensin II to the AT1 receptor, leading to vasodilation and reduced secretion of aldosterone, thereby lowering blood pressure. Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, contributing to decreased blood volume and further reduction in blood pressure. The combined action of these agents provides an effective antihypertensive effect, improving blood pressure control in patients inadequately managed with monotherapy. Irovel H is indicated for the treatment of essential hypertension and may reduce the risk of cardiovascular events associated with high blood pressure. It is generally well tolerated; however, monitoring of renal function, electrolytes, and blood pressure is recommended during therapy. Contraindications include hypersensitivity to either component, severe renal impairment, and anuria. Use in pregnancy is not advised due to potential fetal risk. Patients should adhere to prescribed dosages and consult healthcare professionals regarding any adverse effects or drug interactions.
How to use Irovel H Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Irovel H Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Irovel H Tablet may cause excessive drowsiness with alcohol.
High Risk
Irovel H Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Irovel H Tablet should be used with caution in patients with liver disease. Dose adjustment of Irovel H Tablet may be needed. Please consult your doctor.
Regular Checkup
Irovel H Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Irovel H Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Irovel H Tablet may be needed. Please consult your doctor. Use of Irovel H Tablet is not recommended in patients with severe kidney disease.
Regular Checkup
0 reviews for Irovel H Tablet















