Instgra Tablet
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Bottle of 30 tablets • TabletPrescription requiredSchedule H
Instgra Tablet
Dolutegravir (50mg)
₹3789.40
Bottle of 30 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Dolutegravir 50 mg
How It Works
Dolutegravir inhibits the integrase enzyme, preventing the integration of viral DNA into the host genome, thereby blocking HIV replication.
Medicine Strength
50 mg
Uses & Benefits
Medical applications
HeadacheInfectionViralNausea
Instgra Tablet contains Dolutegravir 50 mg, an antiretroviral medication used in the treatment of Human Immunodeficiency Virus type 1 (HIV-1) infection. Dolutegravir is an integrase strand transfer inhibitor (INSTI) that works by blocking the HIV integrase enzyme, preventing viral DNA from integrating into the host cell genome, thereby inhibiting viral replication. Instgra is typically prescribed as part of combination antiretroviral therapy (cART) to enhance efficacy and reduce the likelihood of resistance development.
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It is indicated for use in treatment-naïve and treatment-experienced adult patients with HIV-1 infection. The recommended dosage is one tablet taken orally once daily, with or without food. Instgra has demonstrated a favorable safety profile, with common adverse effects including insomnia, headache, and gastrointestinal disturbances such as nausea and diarrhea. Caution is advised in patients with hepatic impairment and those on concomitant medications that may interact via the UGT1A1 or CYP3A metabolic pathways.
Regular monitoring of viral load and CD4 counts is essential to assess therapeutic response. Instgra should be used under medical supervision, with adherence to prescribed regimens to optimize treatment outcomes and minimize resistance development.
Dosage & How to Use
How to use Instgra Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Instgra Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Instgra Tablet. Please consult your doctor.
High Risk
Driving
Instgra Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Liver
Instgra Tablet should be used with caution in patients with liver disease. Dose adjustment of Instgra Tablet may be needed. Please consult your doctor.
Regular Checkup
Breastfeeding
Instgra Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consult Doctor
Kidney
Instgra Tablet is safe to use in patients with kidney disease. No dose adjustment of Instgra Tablet is recommended.
Regular Checkup
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