Ibrunat Capsule
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Bottle of 30 capsules • CapsulePrescription requiredSchedule H
Ibrunat Capsule
Ibrutinib (140mg)
₹9500.00
Bottle of 30 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
Ibrutinib 140 mg
How It Works
Ibrutinib inhibits Bruton's tyrosine kinase, disrupting signaling pathways that promote survival and proliferation of malignant B-cells.
Medicine Strength
140 mg
Uses & Benefits
Medical applications
Infection
Ibrunat Capsule contains Ibrutinib 140 mg, a potent Bruton’s tyrosine kinase (BTK) inhibitor indicated for the treatment of various B-cell malignancies, including mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), and Waldenström’s macroglobulinemia (WM). Ibrutinib selectively binds to BTK, a critical enzyme involved in B-cell receptor signaling, thereby inhibiting malignant B-cell proliferation and survival.
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This targeted mechanism of action results in decreased tumor growth and improved patient outcomes. Ibrunat is administered orally, allowing convenient dosing and improved patient compliance. Clinical studies have demonstrated its efficacy in both treatment-naïve and relapsed/refractory patients, with significant improvements in progression-free survival and overall response rates.
Common adverse effects include diarrhea, fatigue, neutropenia, thrombocytopenia, and infections, necessitating regular monitoring of blood counts and clinical status during therapy. Dose adjustments may be required in cases of severe toxicity. Ibrunat should be used under strict medical supervision, particularly in patients with bleeding risks or concomitant anticoagulant therapy, due to potential hemorrhagic complications.
It is contraindicated in patients with known hypersensitivity to Ibrutinib or its excipients. Overall, Ibrunat Capsule represents a valuable therapeutic option in the management of B-cell malignancies, offering targeted efficacy with an acceptable safety profile.
Dosage & How to Use
How to use Ibrunat Capsule Take this medicine in the dose and duration as advised by your doctor. Ibrunat Capsule may be taken with or without food, but it is better to take it at a fixed time.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is not known whether it is safe to consume alcohol with Ibrunat Capsule. Please consult your doctor.
High Risk
Driving
Ibrunat Capsule may cause side effects which could affect your ability to drive.
Exercise Caution
Liver
Ibrunat Capsule should be used with caution in patients with liver disease. Dose adjustment of Ibrunat Capsule may be needed. Please consult your doctor.
Regular Checkup
Breastfeeding
Ibrunat Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Kidney
Ibrunat Capsule should be used with caution in patients with kidney disease. Dose adjustment of Ibrunat Capsule may be needed. Please consult your doctor.
Regular Checkup
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