
Montelukast (10mg) + Doxofylline (400mg)
Active composition
+1 more active ingredient
Montelukast selectively antagonizes leukotriene receptors, inhibiting their effects on bronchoconstriction and inflammation.
Doxofylline inhibits phosphodiesterase, increasing cAMP levels, which leads to relaxation of bronchial smooth muscle and dilation of airways.
Medical applications
Havodil-M Tablet SR is a combination medication containing Doxofylline 400 mg and Montelukast 10 mg, formulated for sustained release to provide prolonged therapeutic effects. Doxofylline, a xanthine derivative, acts as a bronchodilator by inhibiting phosphodiesterase enzymes, leading to relaxation of bronchial smooth muscles and improved airflow in obstructive airway diseases. Montelukast, a leukotriene receptor antagonist, selectively blocks cysteinyl leukotriene receptors, thereby reducing inflammation, bronchoconstriction, and mucus secretion associated with asthma and allergic rhinitis. This combination is indicated for the management and prevention of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD), where both bronchospasm and inflammatory pathways contribute to symptomatology. Havodil-M Tablet SR is designed to improve pulmonary function, reduce the frequency and severity of exacerbations, and enhance patient quality of life. The sustained-release formulation ensures steady plasma concentration, minimizing dosing frequency and improving compliance. It is generally well tolerated; however, clinicians should monitor for potential side effects including headache, gastrointestinal disturbances, and hypersensitivity reactions. Caution is advised in patients with hepatic or renal impairment, and concurrent use with other xanthines or leukotriene modifiers should be carefully evaluated. Havodil-M Tablet SR should be used under medical supervision with appropriate monitoring.
How to use Havodil-M Tablet SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Havodil-M Tablet SR may be taken with or without food, but it is better to take it at a fixed time. Avoid Havodil-M Tablet SR with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Havodil-M Tablet SR. Please consult your doctor.
High Risk
Information regarding the use of Havodil-M Tablet SR during pregnancy is not available. Please consult your doctor.
Medical Advice
Havodil-M Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Havodil-M Tablet SR should be used with caution in patients with severe liver disease. Dose adjustment of Havodil-M Tablet SR may be needed. Please consult your doctor. Limited information is available on the use of Havodil-M Tablet SR in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Regular Checkup
Havodil-M Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
There is limited information available on the use of Havodil-M Tablet SR in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Havodil-M Tablet SR

Doxofylline (400mg) + Montelukast (10mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Montelukast selectively antagonizes leukotriene receptors, inhibiting their effects on bronchoconstriction and inflammation.
Doxofylline inhibits phosphodiesterase, increasing cAMP levels, which leads to relaxation of bronchial smooth muscle and dilation of airways.
Medical applications
Havodil-M Tablet SR is a combination medication containing Doxofylline 400 mg and Montelukast 10 mg, formulated for sustained release to provide prolonged therapeutic effects. Doxofylline, a xanthine derivative, acts as a bronchodilator by inhibiting phosphodiesterase enzymes, leading to relaxation of bronchial smooth muscles and improved airflow in obstructive airway diseases. Montelukast, a leukotriene receptor antagonist, selectively blocks cysteinyl leukotriene receptors, thereby reducing inflammation, bronchoconstriction, and mucus secretion associated with asthma and allergic rhinitis. This combination is indicated for the management and prevention of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD), where both bronchospasm and inflammatory pathways contribute to symptomatology. Havodil-M Tablet SR is designed to improve pulmonary function, reduce the frequency and severity of exacerbations, and enhance patient quality of life. The sustained-release formulation ensures steady plasma concentration, minimizing dosing frequency and improving compliance. It is generally well tolerated; however, clinicians should monitor for potential side effects including headache, gastrointestinal disturbances, and hypersensitivity reactions. Caution is advised in patients with hepatic or renal impairment, and concurrent use with other xanthines or leukotriene modifiers should be carefully evaluated. Havodil-M Tablet SR should be used under medical supervision with appropriate monitoring.
How to use Havodil-M Tablet SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Havodil-M Tablet SR may be taken with or without food, but it is better to take it at a fixed time. Avoid Havodil-M Tablet SR with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Havodil-M Tablet SR. Please consult your doctor.
High Risk
Information regarding the use of Havodil-M Tablet SR during pregnancy is not available. Please consult your doctor.
Medical Advice
Havodil-M Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Havodil-M Tablet SR should be used with caution in patients with severe liver disease. Dose adjustment of Havodil-M Tablet SR may be needed. Please consult your doctor. Limited information is available on the use of Havodil-M Tablet SR in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Regular Checkup
Havodil-M Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
There is limited information available on the use of Havodil-M Tablet SR in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Havodil-M Tablet SR















