
Flunarizine (10mg) + Propranolol (40mg)
Active composition
+1 more active ingredient
Flunarizine acts as a calcium channel blocker, preventing vasodilation and reducing the frequency of migraine attacks.
Propranolol blocks beta-1 and beta-2 adrenergic receptors, resulting in decreased heart rate, myocardial contractility, and overall cardiac output.
Medical applications
Graincide Tablet SR is a combination medication containing Propranolol 40 mg and Flunarizine 10 mg, formulated for sustained release to provide prolonged therapeutic effects. Propranolol is a non-selective beta-adrenergic blocker that reduces heart rate, myocardial contractility, and blood pressure, thereby decreasing cardiac workload and oxygen demand. It is commonly used in the management of hypertension, angina pectoris, arrhythmias, and prevention of migraine. Flunarizine is a calcium channel blocker with antihistaminic properties, effective in the prophylaxis of migraine and treatment of vertigo by inhibiting calcium influx into vascular smooth muscle and neurons, stabilizing neuronal excitability. The combination of these two agents in Graincide Tablet SR offers a dual approach in the prevention of migraine headaches, addressing both vascular and neurological components. This medication is indicated for patients requiring long-term migraine prophylaxis, especially those with concurrent cardiovascular conditions benefiting from beta-blockade. Graincide Tablet SR should be administered as directed by a healthcare professional, with caution advised in patients with asthma, bradycardia, hypotension, or hepatic impairment. Common side effects may include fatigue, dizziness, gastrointestinal disturbances, and cold extremities. Regular monitoring is recommended to assess therapeutic response and detect potential adverse effects.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Graincide Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of Graincide Tablet SR during breastfeeding is not available. Please consult your doctor.
Medical Advice
Graincide Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Graincide Tablet SR may be needed. Please consult your doctor.
Exercise Caution
It is not known whether Graincide Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Graincide Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Graincide Tablet SR may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment.
Regular Checkup
0 reviews for Graincide Tablet SR

Propranolol (40mg) + Flunarizine (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Flunarizine acts as a calcium channel blocker, preventing vasodilation and reducing the frequency of migraine attacks.
Propranolol blocks beta-1 and beta-2 adrenergic receptors, resulting in decreased heart rate, myocardial contractility, and overall cardiac output.
Medical applications
Graincide Tablet SR is a combination medication containing Propranolol 40 mg and Flunarizine 10 mg, formulated for sustained release to provide prolonged therapeutic effects. Propranolol is a non-selective beta-adrenergic blocker that reduces heart rate, myocardial contractility, and blood pressure, thereby decreasing cardiac workload and oxygen demand. It is commonly used in the management of hypertension, angina pectoris, arrhythmias, and prevention of migraine. Flunarizine is a calcium channel blocker with antihistaminic properties, effective in the prophylaxis of migraine and treatment of vertigo by inhibiting calcium influx into vascular smooth muscle and neurons, stabilizing neuronal excitability. The combination of these two agents in Graincide Tablet SR offers a dual approach in the prevention of migraine headaches, addressing both vascular and neurological components. This medication is indicated for patients requiring long-term migraine prophylaxis, especially those with concurrent cardiovascular conditions benefiting from beta-blockade. Graincide Tablet SR should be administered as directed by a healthcare professional, with caution advised in patients with asthma, bradycardia, hypotension, or hepatic impairment. Common side effects may include fatigue, dizziness, gastrointestinal disturbances, and cold extremities. Regular monitoring is recommended to assess therapeutic response and detect potential adverse effects.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Graincide Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of Graincide Tablet SR during breastfeeding is not available. Please consult your doctor.
Medical Advice
Graincide Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Graincide Tablet SR may be needed. Please consult your doctor.
Exercise Caution
It is not known whether Graincide Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Graincide Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Graincide Tablet SR may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment.
Regular Checkup
0 reviews for Graincide Tablet SR















