Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER
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Amlodipine (5mg) + Metoprolol Succinate (23.75mg)
1 units • Other
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Amlodipine inhibits calcium ion influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced myocardial oxygen demand.
Metoprolol Succinate blocks beta-1 adrenergic receptors, leading to decreased heart rate and contractility, thereby lowering blood pressure.
Medical applications
Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER is a combination antihypertensive medication formulated to manage hypertension and angina pectoris. Each extended-release tablet contains 5 mg of amlodipine, a calcium channel blocker that inhibits calcium ion influx into vascular smooth muscle and cardiac muscle, promoting vasodilation and reducing peripheral vascular resistance.
The formulation also includes 23.75 mg of metoprolol succinate, a selective beta-1 adrenergic receptor blocker that decreases heart rate, myocardial contractility, and cardiac output, thereby lowering blood pressure and myocardial oxygen demand. This combination provides complementary mechanisms of action, enhancing blood pressure control and reducing cardiovascular risk. The extended-release formulation ensures a steady plasma concentration, improving patient compliance through once-daily dosing.
Genericart Amlodipine Besylate+Metoprolol Succinate is indicated for the treatment of essential hypertension, stable angina, and other cardiovascular conditions where dual blockade is beneficial. Caution is advised in patients with bradycardia, heart block, or severe hepatic impairment. Common adverse effects may include dizziness, fatigue, and peripheral edema. This medication should be used under medical supervision with regular monitoring of blood pressure, heart rate, and clinical response to optimize therapeutic outcomes.
How to use Genericart Tablet ER Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
It is unsafe to consume alcohol with Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER.
High Risk
Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER may cause side effects which could affect your ability to drive. Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.
Exercise Caution
Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER may be needed. Please consult your doctor.
Regular Checkup
Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER is safe to use in patients with kidney disease. No dose adjustment of Genericart Amlodipine Besylate+Metoprolol Succinate 5mg/25mg Tablet ER is recommended.
Regular Checkup
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