Exemestane is an aromatase inhibitor used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by blocking the aromatase enzyme, which converts androgens to estrogens, thereby lowering estrogen levels in the body. This reduction in estrogen helps prevent the growth of estrogen-dependent tumors. In summary, Exemestane is effective in treating certain types of breast cancer.
Exemestane irreversibly inhibits aromatase, reducing estrogen production and thereby slowing the growth of estrogen-sensitive tumors.