
Nicorandil (5mg)
Active composition
Nicorandil activates potassium channels in vascular smooth muscle, leading to vasodilation and reduced myocardial oxygen demand.
Medical applications
Zynicor 5 Tablet contains Nicorandil 5mg, a vasodilatory agent used primarily in the management of angina pectoris. Nicorandil acts by dual mechanisms: it functions as a nitrate donor, releasing nitric oxide to induce vasodilation of both arterial and venous vessels, and it opens ATP-sensitive potassium channels in vascular smooth muscle, leading to hyperpolarization and relaxation. This combined action results in decreased myocardial oxygen demand through reduction of preload and afterload, thereby alleviating symptoms of angina. Zynicor 5 is indicated for the prophylactic treatment of chronic stable angina and may be used when conventional antianginal therapies are insufficient or contraindicated. The recommended dosage should be individualized based on clinical response and tolerability, with careful monitoring for adverse effects such as headache, dizziness, flushing, and gastrointestinal disturbances. Caution is advised in patients with hypotension, severe renal or hepatic impairment, and those concurrently using other vasodilators or phosphodiesterase inhibitors. Zynicor 5 should be administered under medical supervision, and patients should be advised to report any signs of hypotension or allergic reactions promptly. This medication contributes to improved exercise tolerance and quality of life in patients with ischemic heart disease.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
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Nicorandil (5mg)
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Active composition
Nicorandil activates potassium channels in vascular smooth muscle, leading to vasodilation and reduced myocardial oxygen demand.
Medical applications
Zynicor 5 Tablet contains Nicorandil 5mg, a vasodilatory agent used primarily in the management of angina pectoris. Nicorandil acts by dual mechanisms: it functions as a nitrate donor, releasing nitric oxide to induce vasodilation of both arterial and venous vessels, and it opens ATP-sensitive potassium channels in vascular smooth muscle, leading to hyperpolarization and relaxation. This combined action results in decreased myocardial oxygen demand through reduction of preload and afterload, thereby alleviating symptoms of angina. Zynicor 5 is indicated for the prophylactic treatment of chronic stable angina and may be used when conventional antianginal therapies are insufficient or contraindicated. The recommended dosage should be individualized based on clinical response and tolerability, with careful monitoring for adverse effects such as headache, dizziness, flushing, and gastrointestinal disturbances. Caution is advised in patients with hypotension, severe renal or hepatic impairment, and those concurrently using other vasodilators or phosphodiesterase inhibitors. Zynicor 5 should be administered under medical supervision, and patients should be advised to report any signs of hypotension or allergic reactions promptly. This medication contributes to improved exercise tolerance and quality of life in patients with ischemic heart disease.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
0 reviews for Zynicor 5 Tablet















