
Paracetamol (325mg) + Aceclofenac (100mg) + Tramadol (37.5mg)
Active composition
+2 more active ingredients
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Aceclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which are responsible for pain and inflammation.
Tramadol binds to mu-opioid receptors and inhibits the reuptake of norepinephrine and serotonin, modulating pain perception.
Medical applications
Zerodol PT Tablet is a combination analgesic formulation containing Aceclofenac 100 mg, Paracetamol 325 mg, and Tramadol 37.5 mg, designed for the effective management of moderate to severe pain and inflammation. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), exerts its effect by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis which leads to decreased inflammation and pain. Paracetamol acts centrally to alleviate pain and reduce fever through inhibition of prostaglandin synthesis in the central nervous system. Tramadol, a centrally acting opioid analgesic, provides additional pain relief by binding to mu-opioid receptors and inhibiting the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. This combination is particularly beneficial in conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal disorders, postoperative pain, and other painful inflammatory conditions. Zerodol PT offers synergistic analgesic and anti-inflammatory effects while minimizing the dose-related adverse effects associated with individual components. It should be used under medical supervision, with caution in patients with hepatic, renal, or cardiovascular impairment, and avoided in individuals with hypersensitivity to any of its constituents. Common side effects may include gastrointestinal discomfort, dizziness, and nausea. Proper adherence to prescribed dosage is essential to maximize therapeutic benefits and minimize risks.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
0 reviews for Zerodol PT Tablet

Aceclofenac (100mg) + Paracetamol (325mg) + Tramadol (37.5mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+2 more active ingredients
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Aceclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which are responsible for pain and inflammation.
Tramadol binds to mu-opioid receptors and inhibits the reuptake of norepinephrine and serotonin, modulating pain perception.
Medical applications
Zerodol PT Tablet is a combination analgesic formulation containing Aceclofenac 100 mg, Paracetamol 325 mg, and Tramadol 37.5 mg, designed for the effective management of moderate to severe pain and inflammation. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), exerts its effect by inhibiting cyclooxygenase enzymes, thereby reducing prostaglandin synthesis which leads to decreased inflammation and pain. Paracetamol acts centrally to alleviate pain and reduce fever through inhibition of prostaglandin synthesis in the central nervous system. Tramadol, a centrally acting opioid analgesic, provides additional pain relief by binding to mu-opioid receptors and inhibiting the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. This combination is particularly beneficial in conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal disorders, postoperative pain, and other painful inflammatory conditions. Zerodol PT offers synergistic analgesic and anti-inflammatory effects while minimizing the dose-related adverse effects associated with individual components. It should be used under medical supervision, with caution in patients with hepatic, renal, or cardiovascular impairment, and avoided in individuals with hypersensitivity to any of its constituents. Common side effects may include gastrointestinal discomfort, dizziness, and nausea. Proper adherence to prescribed dosage is essential to maximize therapeutic benefits and minimize risks.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
0 reviews for Zerodol PT Tablet











