Zanocin OZ Tablet
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Ofloxacin (200mg) + Ornidazole (500mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Medical applications
Zanocin OZ Tablet is a combination antibiotic formulation containing Ofloxacin 200 mg and Ornidazole 500 mg, designed for the treatment of mixed bacterial and protozoal infections. Ofloxacin, a fluoroquinolone antibiotic, exerts its bactericidal action by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing DNA replication and transcription in susceptible organisms.
Ornidazole, a nitroimidazole derivative, is effective against anaerobic bacteria and protozoa by causing DNA strand breakage and inhibiting nucleic acid synthesis. This dual-action tablet is commonly prescribed for infections involving both aerobic and anaerobic pathogens, such as gastrointestinal infections, genitourinary tract infections, intra-abdominal infections, and certain sexually transmitted diseases.
Zanocin OZ is particularly useful in treating conditions like bacterial dysentery, amoebiasis, trichomoniasis, and mixed aerobic-anaerobic infections where monotherapy may be insufficient. The combination enhances therapeutic efficacy and reduces the risk of resistance development. Dosage and duration of therapy should be determined by a healthcare professional based on the severity and type of infection.
Patients should use Zanocin OZ with caution if they have a history of hypersensitivity to fluoroquinolones or nitroimidazoles, and it is contraindicated during pregnancy and lactation. Adverse effects may include gastrointestinal disturbances, dizziness, and hypersensitivity reactions.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Safety information not available for this product. Please consult your doctor or pharmacist.
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