Ofloxamac Eye/Ear Drops
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Ofloxacin (NA)
Packet of 10 ml • Liquid
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Active composition
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Medical applications
Ofloxamac Eye/Ear Drops contain Ofloxacin (NA), a broad-spectrum fluoroquinolone antibiotic effective against a wide range of Gram-positive and Gram-negative bacterial pathogens. This formulation is indicated for the treatment of bacterial infections of the eye and ear, including conjunctivitis, keratitis, blepharitis, otitis externa, and otitis media. Ofloxacin exerts its antibacterial activity by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair, thereby preventing bacterial cell proliferation.
The drops are designed for topical administration, ensuring high local concentrations at the site of infection with minimal systemic absorption. Ofloxamac Eye/Ear Drops are generally well tolerated; however, patients may experience mild transient irritation, burning, or discomfort upon instillation. It is contraindicated in individuals with known hypersensitivity to ofloxacin or other quinolones.
Caution is advised in patients with a history of tendon disorders related to quinolone use. Proper administration technique should be followed to avoid contamination and ensure efficacy. Treatment duration should be adhered to as prescribed to prevent resistance development. Ofloxamac Eye/Ear Drops provide an effective therapeutic option for managing bacterial infections of the ocular and aural regions, promoting rapid resolution of symptoms and restoration of normal function.
Fluoroquinolone
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Ofloxamac Eye/Ear Drops may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Ofloxamac Eye/Ear Drops is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
No interaction found/established
Exercise Caution
Ofloxamac Eye/Ear Drops may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
No interaction found/established
Regular Checkup
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