Ofla OZ Tablet
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Ofloxacin (200mg) + Ornidazole (500mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Medical applications
Ofla OZ Tablet is a combination antibiotic formulation containing Ofloxacin 200 mg and Ornidazole 500 mg, indicated for the treatment of mixed bacterial and protozoal infections. Ofloxacin, a fluoroquinolone antibiotic, exerts bactericidal action by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial DNA replication and transcription. Ornidazole, a nitroimidazole derivative, is effective against anaerobic bacteria and protozoa by disrupting DNA synthesis and causing cell death.
This synergistic combination is particularly useful in managing complicated infections such as gastrointestinal infections, genitourinary tract infections, respiratory tract infections, and certain sexually transmitted infections where mixed aerobic and anaerobic pathogens are suspected. Ofla OZ Tablet is prescribed to ensure broad-spectrum antimicrobial coverage, reducing the risk of resistance development and improving therapeutic outcomes.
It is essential to use this medication under medical supervision, adhering to the prescribed dosage and duration to prevent adverse effects and resistance. Common side effects may include gastrointestinal disturbances, headache, dizziness, and hypersensitivity reactions. Caution is advised in patients with a history of hypersensitivity to fluoroquinolones or nitroimidazoles, as well as those with hepatic or renal impairment.
Ofla OZ Tablet should be avoided during pregnancy and lactation unless deemed necessary by a healthcare professional.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Ofla OZ Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of Ofla OZ Tablet during breastfeeding is not available. Please consult your doctor.
Medical Advice
Ofla OZ Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Ofla OZ Tablet may be needed. Please consult your doctor.
Exercise Caution
Ofla OZ Tablet may cause side effects which could affect your ability to drive.
Consult Doctor
Ofla OZ Tablet should be used with caution in patients with liver disease. Dose adjustment of Ofla OZ Tablet may be needed. Please consult your doctor.
Regular Checkup
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