
Ofloxacin (50mg) + Simethicone (10mg) + Metronidazole (100mg)
Active composition
+2 more active ingredients
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Simethicone decreases the surface tension of gas bubbles in the gastrointestinal tract, facilitating their expulsion and alleviating bloating and discomfort.
Metronidazole disrupts DNA synthesis in anaerobic bacteria and protozoa, leading to their death.
Medical applications
Ofkiz-M Oral Suspension Mixed Fruit is a combination antibiotic and antiflatulent formulation containing Ofloxacin (50 mg), Metronidazole (100 mg), and Simethicone (10 mg) per dose. Ofloxacin, a fluoroquinolone antibiotic, exhibits broad-spectrum bactericidal activity by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial replication. Metronidazole is an effective nitroimidazole antimicrobial agent targeting anaerobic bacteria and protozoa through disruption of DNA synthesis. Simethicone acts as an anti-foaming agent that reduces bloating and discomfort caused by excess gas in the gastrointestinal tract by coalescing gas bubbles, facilitating their elimination. This oral suspension is indicated for the treatment of mixed bacterial infections of the gastrointestinal tract, including amoebiasis, giardiasis, and bacterial diarrhea, where both aerobic and anaerobic pathogens are suspected, accompanied by symptoms of abdominal distension and flatulence. The mixed fruit flavor enhances palatability, improving patient compliance, especially in pediatric and geriatric populations. Dosage should be administered as prescribed by a healthcare professional, considering the patient’s age, weight, and severity of infection. Caution is advised in patients with hypersensitivity to fluoroquinolones, nitroimidazoles, or simethicone, and in those with hepatic or renal impairment. Adverse effects may include gastrointestinal disturbances, headache, dizziness, and hypersensitivity reactions.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Ofkiz-M Oral Suspension Mixed Fruit should be used with caution in patients with kidney disease. Dose adjustment of Ofkiz-M Oral Suspension Mixed Fruit may be needed. Please consult your doctor.
Exercise Caution
Ofkiz-M Oral Suspension Mixed Fruit should be used with caution in patients with severe liver disease. Dose adjustment of Ofkiz-M Oral Suspension Mixed Fruit may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Ofkiz-M Oral Suspension Mixed Fruit

Ofloxacin (50mg) + Metronidazole (100mg) + Simethicone (10mg)
Cheaper alternative availability
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Active composition
+2 more active ingredients
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Simethicone decreases the surface tension of gas bubbles in the gastrointestinal tract, facilitating their expulsion and alleviating bloating and discomfort.
Metronidazole disrupts DNA synthesis in anaerobic bacteria and protozoa, leading to their death.
Medical applications
Ofkiz-M Oral Suspension Mixed Fruit is a combination antibiotic and antiflatulent formulation containing Ofloxacin (50 mg), Metronidazole (100 mg), and Simethicone (10 mg) per dose. Ofloxacin, a fluoroquinolone antibiotic, exhibits broad-spectrum bactericidal activity by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing bacterial replication. Metronidazole is an effective nitroimidazole antimicrobial agent targeting anaerobic bacteria and protozoa through disruption of DNA synthesis. Simethicone acts as an anti-foaming agent that reduces bloating and discomfort caused by excess gas in the gastrointestinal tract by coalescing gas bubbles, facilitating their elimination. This oral suspension is indicated for the treatment of mixed bacterial infections of the gastrointestinal tract, including amoebiasis, giardiasis, and bacterial diarrhea, where both aerobic and anaerobic pathogens are suspected, accompanied by symptoms of abdominal distension and flatulence. The mixed fruit flavor enhances palatability, improving patient compliance, especially in pediatric and geriatric populations. Dosage should be administered as prescribed by a healthcare professional, considering the patient’s age, weight, and severity of infection. Caution is advised in patients with hypersensitivity to fluoroquinolones, nitroimidazoles, or simethicone, and in those with hepatic or renal impairment. Adverse effects may include gastrointestinal disturbances, headache, dizziness, and hypersensitivity reactions.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Ofkiz-M Oral Suspension Mixed Fruit should be used with caution in patients with kidney disease. Dose adjustment of Ofkiz-M Oral Suspension Mixed Fruit may be needed. Please consult your doctor.
Exercise Caution
Ofkiz-M Oral Suspension Mixed Fruit should be used with caution in patients with severe liver disease. Dose adjustment of Ofkiz-M Oral Suspension Mixed Fruit may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Ofkiz-M Oral Suspension Mixed Fruit















