Office 100 mg/100 mg Tablet
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Cefixime (100mg) + Ofloxacin (100mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Cefixime disrupts the synthesis of the bacterial cell wall, leading to bacterial lysis and death.
Medical applications
Office 100 mg/100 mg Tablet is a combination antibiotic formulation containing Cefixime 100 mg and Ofloxacin 100 mg, designed for the treatment of a wide range of bacterial infections. Cefixime, a third-generation cephalosporin, acts by inhibiting bacterial cell wall synthesis, leading to cell lysis and death, while Ofloxacin, a fluoroquinolone, interferes with bacterial DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and transcription.
This synergistic action enhances the antibacterial spectrum, making Office effective against both Gram-positive and Gram-negative pathogens. It is commonly prescribed for urinary tract infections, respiratory tract infections, gastrointestinal infections, and sexually transmitted infections caused by susceptible organisms. The combination therapy helps reduce the risk of resistance development and improves clinical outcomes.
Office 100 mg/100 mg Tablet should be used under medical supervision, with dosage and duration tailored according to the severity and type of infection. Caution is advised in patients with a history of hypersensitivity to cephalosporins or fluoroquinolones, and it is contraindicated in individuals with known tendon disorders related to fluoroquinolone use. Common adverse effects may include gastrointestinal disturbances, headache, dizziness, and hypersensitivity reactions.
Complete the full prescribed course to prevent recurrence and resistance.
How can I give Office 100 mg/100 mg Tablet to my child? Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Office 100 mg/100 mg Tablet is to be taken with food.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Office 100 mg/100 mg Tablet is safe to use in patients with liver disease. No dose adjustment of Office 100 mg/100 mg Tablet is recommended. However, consult your child’s doctor before giving $med_name to your child in case of a severe form of liver disease.
Regular Checkup
Office 100 mg/100 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Office 100 mg/100 mg Tablet may be needed. Please consult your doctor.
Regular Checkup
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