
Ofloxacin (200mg) + Ornidazole (500mg)
Active composition
+1 more active ingredient
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Medical applications
Off Doc 200mg/500mg Tablet is a combination antibiotic formulation containing Ofloxacin 200mg and Ornidazole 500mg, designed for the treatment of a broad spectrum of bacterial and protozoal infections. Ofloxacin, a fluoroquinolone antibiotic, exerts its bactericidal action by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing DNA replication and transcription in susceptible organisms. Ornidazole, a nitroimidazole derivative, is effective against anaerobic bacteria and protozoa by causing DNA strand breakage and inhibition of nucleic acid synthesis. This synergistic combination is particularly useful in managing mixed infections involving both aerobic and anaerobic pathogens, such as gastrointestinal infections, genitourinary tract infections, respiratory tract infections, and certain sexually transmitted infections. Off Doc tablets should be administered as prescribed by a healthcare professional, with dosage adjusted according to the severity of infection and patient-specific factors including renal function. Caution is advised in patients with a history of hypersensitivity to fluoroquinolones or nitroimidazoles, and potential side effects may include gastrointestinal disturbances, dizziness, and hypersensitivity reactions. Complete the full course of therapy to prevent resistance development and ensure optimal clinical outcomes.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Off Doc 200mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of Off Doc 200mg/500mg Tablet during breastfeeding is not available. Please consult your doctor.
Medical Advice
Off Doc 200mg/500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Off Doc 200mg/500mg Tablet may be needed. Please consult your doctor.
Exercise Caution
Off Doc 200mg/500mg Tablet may cause side effects which could affect your ability to drive.
Consult Doctor
Off Doc 200mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Off Doc 200mg/500mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Off Doc 200mg/500mg Tablet

Ofloxacin (200mg) + Ornidazole (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Ofloxacin inhibits DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Ornidazole disrupts DNA synthesis in protozoan organisms, leading to cell death and resolution of infection.
Medical applications
Off Doc 200mg/500mg Tablet is a combination antibiotic formulation containing Ofloxacin 200mg and Ornidazole 500mg, designed for the treatment of a broad spectrum of bacterial and protozoal infections. Ofloxacin, a fluoroquinolone antibiotic, exerts its bactericidal action by inhibiting bacterial DNA gyrase and topoisomerase IV, thereby preventing DNA replication and transcription in susceptible organisms. Ornidazole, a nitroimidazole derivative, is effective against anaerobic bacteria and protozoa by causing DNA strand breakage and inhibition of nucleic acid synthesis. This synergistic combination is particularly useful in managing mixed infections involving both aerobic and anaerobic pathogens, such as gastrointestinal infections, genitourinary tract infections, respiratory tract infections, and certain sexually transmitted infections. Off Doc tablets should be administered as prescribed by a healthcare professional, with dosage adjusted according to the severity of infection and patient-specific factors including renal function. Caution is advised in patients with a history of hypersensitivity to fluoroquinolones or nitroimidazoles, and potential side effects may include gastrointestinal disturbances, dizziness, and hypersensitivity reactions. Complete the full course of therapy to prevent resistance development and ensure optimal clinical outcomes.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Off Doc 200mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of Off Doc 200mg/500mg Tablet during breastfeeding is not available. Please consult your doctor.
Medical Advice
Off Doc 200mg/500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Off Doc 200mg/500mg Tablet may be needed. Please consult your doctor.
Exercise Caution
Off Doc 200mg/500mg Tablet may cause side effects which could affect your ability to drive.
Consult Doctor
Off Doc 200mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Off Doc 200mg/500mg Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Off Doc 200mg/500mg Tablet















