Oceva 10mg/ml Injection
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Ranibizumab (10mg/ml)
Vial of 1 injection • Injection
A valid prescription is required for this medicine.
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Active composition
Ranibizumab binds to VEGF-A, blocking its interaction with receptors on endothelial cells, thus inhibiting neovascularization and edema.
Medical applications
Oceva 10mg/ml Injection contains Ranibizumab, a recombinant humanized monoclonal antibody fragment specifically designed to inhibit vascular endothelial growth factor A (VEGF-A). It is indicated for the treatment of neovascular (wet) age-related macular degeneration (AMD), diabetic macular edema (DME), macular edema following retinal vein occlusion (RVO), and other retinal vascular disorders characterized by abnormal angiogenesis and increased vascular permeability.
Ranibizumab acts by binding to VEGF-A isoforms, thereby preventing their interaction with VEGF receptors on the surface of endothelial cells, which results in the inhibition of pathological neovascularization and reduction of vascular leakage. Oceva is administered via intravitreal injection, typically at a dose of 0.5 mg (0.05 ml) per injection, with dosing frequency determined by the treating ophthalmologist based on disease severity and response.
Clinical studies have demonstrated its efficacy in improving visual acuity and reducing retinal thickness in affected patients. Common adverse effects include conjunctival hemorrhage, eye pain, vitreous floaters, and increased intraocular pressure. Proper aseptic technique and patient monitoring are essential to minimize the risk of endophthalmitis and other injection-related complications.
Oceva should be used under specialist supervision with regular ophthalmic evaluations to optimize therapeutic outcomes.
Monoclonal antibody (mAb)
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Oceva 10mg/ml Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Oceva 10mg/ml Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
Oceva 10mg/ml Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Oceva 10mg/ml Injection may not be needed in these patients. Please consult your doctor.
Exercise Caution
Oceva 10mg/ml Injection may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Consult Doctor
Oceva 10mg/ml Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Oceva 10mg/ml Injection may not be needed in these patients. Please consult your doctor.
Regular Checkup
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