
Domperidone (10mg) + Naproxen (500mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Medical applications
Naprosafe-D 500 Tablet is a combination medication containing Naproxen (500mg) and Domperidone (10mg). Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), is primarily used for its analgesic, antipyretic, and anti-inflammatory properties to manage symptoms of various musculoskeletal disorders, rheumatic diseases, and acute pain. Domperidone, a prokinetic agent, aids in the treatment of gastrointestinal disorders characterized by decreased gastric motility, such as diabetic gastroparesis and postoperative ileus. Naprosafe-D 500 Tablet offers a combined therapeutic approach for patients requiring both anti-inflammatory and gastrointestinal supportive therapy. However, due to potential side effects and contraindications, it is essential to consult a healthcare professional before initiating or modifying treatment.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Naprosafe-D 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Naprosafe-D 500 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Naprosafe-D 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Naprosafe-D 500 Tablet may be needed. Please consult your doctor.
Exercise Caution
Naprosafe-D 500 Tablet may cause side effects which could affect your ability to drive. Naprosafe-D 500 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Naprosafe-D 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Naprosafe-D 500 Tablet may be needed. Please consult your doctor. Use of Naprosafe-D 500 Tablet is not recommended in patients with moderate and severe liver disease.
Regular Checkup
0 reviews for Naprosafe-D 500 Tablet

Naproxen (500mg) + Domperidone (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Medical applications
Naprosafe-D 500 Tablet is a combination medication containing Naproxen (500mg) and Domperidone (10mg). Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), is primarily used for its analgesic, antipyretic, and anti-inflammatory properties to manage symptoms of various musculoskeletal disorders, rheumatic diseases, and acute pain. Domperidone, a prokinetic agent, aids in the treatment of gastrointestinal disorders characterized by decreased gastric motility, such as diabetic gastroparesis and postoperative ileus. Naprosafe-D 500 Tablet offers a combined therapeutic approach for patients requiring both anti-inflammatory and gastrointestinal supportive therapy. However, due to potential side effects and contraindications, it is essential to consult a healthcare professional before initiating or modifying treatment.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Naprosafe-D 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Naprosafe-D 500 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Naprosafe-D 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Naprosafe-D 500 Tablet may be needed. Please consult your doctor.
Exercise Caution
Naprosafe-D 500 Tablet may cause side effects which could affect your ability to drive. Naprosafe-D 500 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Naprosafe-D 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Naprosafe-D 500 Tablet may be needed. Please consult your doctor. Use of Naprosafe-D 500 Tablet is not recommended in patients with moderate and severe liver disease.
Regular Checkup
0 reviews for Naprosafe-D 500 Tablet















