
Esomeprazole (20mg) + Naproxen (500mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Medical applications
Esonap Tablet DR is a combination medication containing Naproxen 500 mg and Esomeprazole 20 mg, formulated to provide effective relief from inflammatory conditions while minimizing gastrointestinal side effects. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), exerts analgesic, anti-inflammatory, and antipyretic effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing prostaglandin synthesis. It is commonly used in the management of conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute musculoskeletal pain. However, NSAIDs like Naproxen are associated with an increased risk of gastrointestinal irritation, ulcers, and bleeding. To mitigate these adverse effects, Esomeprazole, a proton pump inhibitor (PPI), is included to suppress gastric acid secretion, promoting mucosal protection and healing. The delayed-release formulation ensures optimal absorption and targeted delivery of Esomeprazole to the intestine, enhancing its efficacy. Esonap Tablet DR should be used under medical supervision, especially in patients with a history of peptic ulcer disease, gastrointestinal bleeding, or renal impairment. Caution is advised in patients with cardiovascular risk factors. This combination therapy provides a balanced approach to managing pain and inflammation while safeguarding the gastrointestinal tract.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Esonap Tablet DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Esonap Tablet DR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Esonap Tablet DR should be used with caution in patients with kidney disease. Dose adjustment of Esonap Tablet DR may be needed. Please consult your doctor.
Exercise Caution
Esonap Tablet DR may cause side effects which could affect your ability to drive. Esonap Tablet DR may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Esonap Tablet DR should be used with caution in patients with liver disease. Dose adjustment of Esonap Tablet DR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esonap Tablet DR

Naproxen (500mg) + Esomeprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Medical applications
Esonap Tablet DR is a combination medication containing Naproxen 500 mg and Esomeprazole 20 mg, formulated to provide effective relief from inflammatory conditions while minimizing gastrointestinal side effects. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), exerts analgesic, anti-inflammatory, and antipyretic effects by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing prostaglandin synthesis. It is commonly used in the management of conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute musculoskeletal pain. However, NSAIDs like Naproxen are associated with an increased risk of gastrointestinal irritation, ulcers, and bleeding. To mitigate these adverse effects, Esomeprazole, a proton pump inhibitor (PPI), is included to suppress gastric acid secretion, promoting mucosal protection and healing. The delayed-release formulation ensures optimal absorption and targeted delivery of Esomeprazole to the intestine, enhancing its efficacy. Esonap Tablet DR should be used under medical supervision, especially in patients with a history of peptic ulcer disease, gastrointestinal bleeding, or renal impairment. Caution is advised in patients with cardiovascular risk factors. This combination therapy provides a balanced approach to managing pain and inflammation while safeguarding the gastrointestinal tract.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Esonap Tablet DR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Esonap Tablet DR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Esonap Tablet DR should be used with caution in patients with kidney disease. Dose adjustment of Esonap Tablet DR may be needed. Please consult your doctor.
Exercise Caution
Esonap Tablet DR may cause side effects which could affect your ability to drive. Esonap Tablet DR may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Esonap Tablet DR should be used with caution in patients with liver disease. Dose adjustment of Esonap Tablet DR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esonap Tablet DR















