
Domperidone (10mg) + Naproxen (500mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Medical applications
Naprexa D 500mg/10mg Tablets are a combination medication, containing Naproxen 500mg and Domperidone 10mg per tablet. Naproxen, a non-steroidal anti-inflammatory drug (NSAID), is primarily used for its analgesic, antipyretic, and anti-inflammatory properties to manage symptoms of various musculoskeletal disorders, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Simultaneously, Domperidone, a prokinetic agent, is employed to alleviate gastrointestinal disorders such as gastroparesis, dyspepsia, and nausea and vomiting. Naprexa D is indicated for patients requiring both analgesia and gastrointestinal symptom relief. As with any medication, it's crucial to consult a healthcare provider for proper dosage, potential drug interactions, and contraindications.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Naprexa D 500mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Naprexa D 500mg/10mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Naprexa D 500mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Naprexa D 500mg/10mg Tablet may be needed. Please consult your doctor.
Exercise Caution
Naprexa D 500mg/10mg Tablet may cause side effects which could affect your ability to drive. Naprexa D 500mg/10mg Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Naprexa D 500mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Naprexa D 500mg/10mg Tablet may be needed. Please consult your doctor. Use of Naprexa D 500mg/10mg Tablet is not recommended in patients with moderate and severe liver disease.
Regular Checkup
0 reviews for Naprexa D 500mg/10mg Tablet

Naproxen (500mg) + Domperidone (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Medical applications
Naprexa D 500mg/10mg Tablets are a combination medication, containing Naproxen 500mg and Domperidone 10mg per tablet. Naproxen, a non-steroidal anti-inflammatory drug (NSAID), is primarily used for its analgesic, antipyretic, and anti-inflammatory properties to manage symptoms of various musculoskeletal disorders, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Simultaneously, Domperidone, a prokinetic agent, is employed to alleviate gastrointestinal disorders such as gastroparesis, dyspepsia, and nausea and vomiting. Naprexa D is indicated for patients requiring both analgesia and gastrointestinal symptom relief. As with any medication, it's crucial to consult a healthcare provider for proper dosage, potential drug interactions, and contraindications.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Naprexa D 500mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Naprexa D 500mg/10mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Naprexa D 500mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Naprexa D 500mg/10mg Tablet may be needed. Please consult your doctor.
Exercise Caution
Naprexa D 500mg/10mg Tablet may cause side effects which could affect your ability to drive. Naprexa D 500mg/10mg Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Naprexa D 500mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Naprexa D 500mg/10mg Tablet may be needed. Please consult your doctor. Use of Naprexa D 500mg/10mg Tablet is not recommended in patients with moderate and severe liver disease.
Regular Checkup
0 reviews for Naprexa D 500mg/10mg Tablet















