
Sulbactam (500mg) + Cefoperazone (1000mg)
Active composition
+1 more active ingredient
Sulbactam irreversibly binds to beta-lactamase enzymes, preventing them from inactivating beta-lactam antibiotics.
Cefoperazone binds to penicillin-binding proteins, disrupting bacterial cell wall synthesis and leading to cell death.
Medical applications
Moncef S 1000mg/500mg Injection is a sterile, lyophilized powder for reconstitution and injection, containing a fixed combination of cefoperazone (1000mg) and sulbactam (500mg). Cefoperazone is a broad-spectrum cephalosporin antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, and Streptococcus pneumoniae. Sulbactam, a β-lactamase inhibitor, enhances the activity of cefoperazone by inhibiting the action of β-lactamases, thereby broadening the spectrum of antimicrobial activity. Moncef S is indicated for the treatment of severe infections, including pneumonia, septicemia, and skin and soft tissue infections, caused by susceptible bacteria. The product should be reconstituted with Sterile Water for Injection and administered intravenously every 8 to 12 hours. As with all antimicrobial agents, use of Moncef S should be based on a thorough understanding of the patient's clinical status, the microbiological diagnosis, and the effectiveness of the treatment.
How to use Moncef S Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol while taking Moncef S 1000mg/500mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
High Risk
Moncef S 1000mg/500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Medical Advice
It is not known whether Moncef S 1000mg/500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
There is limited information available on the use of Moncef S 1000mg/500mg Injection in patients with liver disease. Please consult your doctor.
Regular Checkup
Moncef S 1000mg/500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Consult Doctor
There is limited information available on the use of Moncef S 1000mg/500mg Injection in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Moncef S 1000mg/500mg Injection

Cefoperazone (1000mg) + Sulbactam (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Sulbactam irreversibly binds to beta-lactamase enzymes, preventing them from inactivating beta-lactam antibiotics.
Cefoperazone binds to penicillin-binding proteins, disrupting bacterial cell wall synthesis and leading to cell death.
Medical applications
Moncef S 1000mg/500mg Injection is a sterile, lyophilized powder for reconstitution and injection, containing a fixed combination of cefoperazone (1000mg) and sulbactam (500mg). Cefoperazone is a broad-spectrum cephalosporin antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, and Streptococcus pneumoniae. Sulbactam, a β-lactamase inhibitor, enhances the activity of cefoperazone by inhibiting the action of β-lactamases, thereby broadening the spectrum of antimicrobial activity. Moncef S is indicated for the treatment of severe infections, including pneumonia, septicemia, and skin and soft tissue infections, caused by susceptible bacteria. The product should be reconstituted with Sterile Water for Injection and administered intravenously every 8 to 12 hours. As with all antimicrobial agents, use of Moncef S should be based on a thorough understanding of the patient's clinical status, the microbiological diagnosis, and the effectiveness of the treatment.
How to use Moncef S Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol while taking Moncef S 1000mg/500mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
High Risk
Moncef S 1000mg/500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Medical Advice
It is not known whether Moncef S 1000mg/500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
There is limited information available on the use of Moncef S 1000mg/500mg Injection in patients with liver disease. Please consult your doctor.
Regular Checkup
Moncef S 1000mg/500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Consult Doctor
There is limited information available on the use of Moncef S 1000mg/500mg Injection in patients with kidney disease. Please consult your doctor.
Regular Checkup
0 reviews for Moncef S 1000mg/500mg Injection















