Mikastar 500 Injection
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Amikacin (500mg)
Vial of 2 ml • Liquid
A valid prescription is required for this medicine.
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Active composition
Medical applications
Mikastar 500 Injection is a sterile, pyrogen-free solution of amikacin sulfate, a broad-spectrum antibiotic, available in a 2 mL ampoule. The product is indicated for the treatment of Gram-negative infections, including pneumonia, septicemia, and urinary tract infections. Amikacin, the active ingredient, inhibits protein synthesis by binding to the 30S ribosomal subunit, thereby disrupting bacterial protein synthesis.
Mikastar 500 Injection is administered intramuscularly or intravenously every 12 hours. The usual dose for adults and pediatric patients is 15 mg/kg, not exceeding 1 g, per day. The duration of therapy should be guided by clinical response and susceptibility testing. Common adverse reactions include vestibular disturbances, tinnitus, and nephrotoxicity. Patients with pre-existing kidney disease or receiving concomitant nephrotoxic medications are at increased risk of developing nephrotoxicity.
Monitoring of renal function and audiological evaluations are recommended during therapy. Mikastar 500 Injection should be used with caution in patients with known or suspected hearing impairment.
How to use Mikastar Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
It is not known whether it is safe to consume alcohol with Mikastar 500 Injection. Please consult your doctor.
High Risk
Mikastar 500 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Mikastar 500 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
There is limited information available on the use of Mikastar 500 Injection in patients with liver disease. Please consult your doctor.
Regular Checkup
Mikastar 500 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Mikastar 500 Injection should be used with caution in patients with kidney disease. Dose adjustment of Mikastar 500 Injection may be needed. Please consult your doctor.
Regular Checkup
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