
Paracetamol (500mg) + Domperidone (10mg) + Flunarizine (5mg)
Active composition
+2 more active ingredients
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Flunarizine acts as a calcium channel blocker, preventing vasodilation and reducing the frequency of migraine attacks.
Medical applications
Migrest Tablet is a proprietary medicinal product designed to provide effective relief from migraine symptoms. Each tablet contains a fixed dose combination of Domperidone (10mg), Flunarizine (5mg), and Paracetamol (500mg). Domperidone, a dopamine antagonist, helps to alleviate nausea and vomiting associated with migraines, while Flunarizine, a calcium channel blocker, exhibits a potent anticonvulsant and anti-inflammatory effect, contributing to its efficacy in reducing migraine pain. Paracetamol, a widely used analgesic and antipyretic, provides additional relief from headache and pain. The triple-combination therapy in Migrest Tablet synergistically targets multiple pathways to provide rapid and sustained relief from migraine symptoms, including pain, nausea, and vomiting. The product is indicated for the treatment of acute migraine attacks and is suitable for adult patients who experience moderate to severe migraine pain. Migrest Tablet is available in a standardized dosage form and should be taken as directed by a healthcare professional.
How to use Migrest Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Migrest Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Migrest Tablet.
High Risk
Migrest Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Migrest Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Migrest Tablet should be used with caution in patients with liver disease. Dose adjustment of Migrest Tablet may be needed. Please consult your doctor. However, the use of Migrest Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Information regarding the use of Migrest Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Migrest Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Migrest Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Migrest Tablet

Domperidone (10mg) + Flunarizine (5mg) + Paracetamol (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+2 more active ingredients
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Flunarizine acts as a calcium channel blocker, preventing vasodilation and reducing the frequency of migraine attacks.
Medical applications
Migrest Tablet is a proprietary medicinal product designed to provide effective relief from migraine symptoms. Each tablet contains a fixed dose combination of Domperidone (10mg), Flunarizine (5mg), and Paracetamol (500mg). Domperidone, a dopamine antagonist, helps to alleviate nausea and vomiting associated with migraines, while Flunarizine, a calcium channel blocker, exhibits a potent anticonvulsant and anti-inflammatory effect, contributing to its efficacy in reducing migraine pain. Paracetamol, a widely used analgesic and antipyretic, provides additional relief from headache and pain. The triple-combination therapy in Migrest Tablet synergistically targets multiple pathways to provide rapid and sustained relief from migraine symptoms, including pain, nausea, and vomiting. The product is indicated for the treatment of acute migraine attacks and is suitable for adult patients who experience moderate to severe migraine pain. Migrest Tablet is available in a standardized dosage form and should be taken as directed by a healthcare professional.
How to use Migrest Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Migrest Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Migrest Tablet.
High Risk
Migrest Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Migrest Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Migrest Tablet should be used with caution in patients with liver disease. Dose adjustment of Migrest Tablet may be needed. Please consult your doctor. However, the use of Migrest Tablet is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
Information regarding the use of Migrest Tablet during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Migrest Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Migrest Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Migrest Tablet















