
Paracetamol (250mg) + Prochlorperazine (2.5mg) + Ergotamine (1mg) + Caffeine (100mg)
Active composition
+3 more active ingredients
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Prochlorperazine inhibits dopamine receptors in the chemoreceptor trigger zone, preventing nausea and vomiting.
Ergotamine stimulates alpha-adrenergic receptors, leading to vasoconstriction and reduced headache symptoms.
Medical applications
Migrafen Tablet is a prescription-only medication indicated for the treatment of migraine, tension headache, and vertigo. Each tablet contains a fixed combination of caffeine (100mg), ergotamine (1mg), paracetamol (250mg), and prochlorperazine (2.5mg). The synergistic effect of these active ingredients provides comprehensive relief from migraine symptoms, including pain, nausea, vomiting, and sensitivity to light and sound. The caffeine and ergotamine components work together to constrict blood vessels, reducing inflammation and pain, while paracetamol provides additional analgesic and antipyretic effects. Prochlorperazine, a dopamine antagonist, helps to alleviate nausea and vomiting. Migrafen Tablet is available in a single strength and should be taken as directed by a healthcare professional, typically one tablet every 30 minutes as needed, up to a maximum of three tablets in a 24-hour period. It is contraindicated in patients with known hypersensitivity to any of the active ingredients, and caution should be exercised in patients with a history of seizures, cardiovascular disease, or impaired hepatic function.
How to use Migrafen Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Migrafen Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Migrafen Tablet.
High Risk
Migrafen Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Migrafen Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Migrafen Tablet should be used with caution in patients with liver disease. Dose adjustment of Migrafen Tablet may be needed. Please consult your doctor.
Regular Checkup
Migrafen Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Occasional short-term use of Migrafen Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.
Consult Doctor
Migrafen Tablet should be used with caution in patients with kidney disease. Dose adjustment of Migrafen Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Migrafen Tablet

Caffeine (100mg) + Ergotamine (1mg) + Paracetamol (250mg) + Prochlorperazine (2.5mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+3 more active ingredients
Paracetamol works by inhibiting cyclooxygenase (COX) enzymes, leading to reduced synthesis of prostaglandins in the brain, which are responsible for pain and fever.
Prochlorperazine inhibits dopamine receptors in the chemoreceptor trigger zone, preventing nausea and vomiting.
Ergotamine stimulates alpha-adrenergic receptors, leading to vasoconstriction and reduced headache symptoms.
Medical applications
Migrafen Tablet is a prescription-only medication indicated for the treatment of migraine, tension headache, and vertigo. Each tablet contains a fixed combination of caffeine (100mg), ergotamine (1mg), paracetamol (250mg), and prochlorperazine (2.5mg). The synergistic effect of these active ingredients provides comprehensive relief from migraine symptoms, including pain, nausea, vomiting, and sensitivity to light and sound. The caffeine and ergotamine components work together to constrict blood vessels, reducing inflammation and pain, while paracetamol provides additional analgesic and antipyretic effects. Prochlorperazine, a dopamine antagonist, helps to alleviate nausea and vomiting. Migrafen Tablet is available in a single strength and should be taken as directed by a healthcare professional, typically one tablet every 30 minutes as needed, up to a maximum of three tablets in a 24-hour period. It is contraindicated in patients with known hypersensitivity to any of the active ingredients, and caution should be exercised in patients with a history of seizures, cardiovascular disease, or impaired hepatic function.
How to use Migrafen Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Migrafen Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Migrafen Tablet.
High Risk
Migrafen Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Migrafen Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Migrafen Tablet should be used with caution in patients with liver disease. Dose adjustment of Migrafen Tablet may be needed. Please consult your doctor.
Regular Checkup
Migrafen Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Occasional short-term use of Migrafen Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.
Consult Doctor
Migrafen Tablet should be used with caution in patients with kidney disease. Dose adjustment of Migrafen Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Migrafen Tablet















