
Glimepiride (1mg) + Metformin (500mg)
Active composition
+1 more active ingredient
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Metsmall G 1mg/500mg Tablet is a fixed-dose combination of Glimepiride (1mg) and Metformin (500mg) indicated for the treatment of type 2 diabetes mellitus, particularly in patients who are unable to achieve adequate glycemic control with metformin alone. Glimepiride, a sulfonylurea, enhances insulin secretion, while Metformin, a biguanide, increases glucose uptake in the peripheral tissues. This combination tablet works by synergistically increasing insulin sensitivity, enhancing glucose metabolism, and improving insulin secretion. Metsmall G is suitable for patients who are not achieving adequate glycemic control with metformin alone, and for those who are intolerant to metformin. It is also indicated for patients with type 2 diabetes who are at risk of developing cardiovascular disease. The recommended starting dose is 1 tablet once daily, with the option to increase to a maximum of 2 tablets once daily. Metsmall G is contraindicated in patients with severe kidney or liver impairment, and those with a history of hypoglycemia.
How to use Metsmall G Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metsmall G 1mg/500mg Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Metsmall G 1mg/500mg Tablet.
High Risk
Metsmall G 1mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Metsmall G 1mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Metsmall G 1mg/500mg Tablet may be needed. Please consult your doctor. Metsmall G 1mg/500mg Tablet is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Metsmall G 1mg/500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Metsmall G 1mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metsmall G 1mg/500mg Tablet may be needed. Please consult your doctor. Use of Metsmall G 1mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Metsmall G 1mg/500mg Tablet

Glimepiride (1mg) + Metformin (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Metsmall G 1mg/500mg Tablet is a fixed-dose combination of Glimepiride (1mg) and Metformin (500mg) indicated for the treatment of type 2 diabetes mellitus, particularly in patients who are unable to achieve adequate glycemic control with metformin alone. Glimepiride, a sulfonylurea, enhances insulin secretion, while Metformin, a biguanide, increases glucose uptake in the peripheral tissues. This combination tablet works by synergistically increasing insulin sensitivity, enhancing glucose metabolism, and improving insulin secretion. Metsmall G is suitable for patients who are not achieving adequate glycemic control with metformin alone, and for those who are intolerant to metformin. It is also indicated for patients with type 2 diabetes who are at risk of developing cardiovascular disease. The recommended starting dose is 1 tablet once daily, with the option to increase to a maximum of 2 tablets once daily. Metsmall G is contraindicated in patients with severe kidney or liver impairment, and those with a history of hypoglycemia.
How to use Metsmall G Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metsmall G 1mg/500mg Tablet is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Metsmall G 1mg/500mg Tablet.
High Risk
Metsmall G 1mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Metsmall G 1mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Metsmall G 1mg/500mg Tablet may be needed. Please consult your doctor. Metsmall G 1mg/500mg Tablet is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Metsmall G 1mg/500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Metsmall G 1mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metsmall G 1mg/500mg Tablet may be needed. Please consult your doctor. Use of Metsmall G 1mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Metsmall G 1mg/500mg Tablet













