SITARAY M 50/500MG TAB
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Sitagliptin (50mg) + Metformin (500mg)
MRP ₹176.00
Strip of 15 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Sitagliptin inhibits DPP-4, increasing incretin levels, which stimulate insulin release and reduce glucagon secretion.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
This medication is used to improve glycemic control in patients with type 2 diabetes mellitus. It is indicated as an adjunct to diet and exercise to lower blood sugar levels, helping to prevent long-term complications associated with chronic hyperglycemia by enhancing insulin secretion and improving insulin sensitivity in the body.
Swallow the tablet whole with a glass of water. Do not crush, chew, or break it. This medicine must be taken with or immediately after meals (usually twice daily, or as prescribed). Taking it with food significantly reduces the risk of common gastrointestinal side effects like stomach upset, nausea, or diarrhea caused by Metformin. Take it consistently at the same times every day. Never stop taking this medication abruptly without consulting your doctor, even if your blood sugar readings normalize.
Important precautions
Do not use if you have severe kidney disease or metabolic acidosis. Discontinue use and seek medical help if you experience symptoms of lactic acidosis, such as unusual muscle pain or difficulty breathing. Regular monitoring of kidney function and blood glucose levels is essential throughout the course of treatment.
Avoid excessive alcohol consumption while taking this medication. Alcohol can increase the risk of lactic acidosis, a rare but serious side effect of metformin. Furthermore, alcohol can cause unpredictable fluctuations in blood sugar levels, making it difficult to manage your diabetes effectively while on this treatment regimen.
High Risk
This medication is generally not recommended during pregnancy. Consult your doctor to discuss safer alternatives, such as insulin therapy, which is often preferred for managing blood glucose levels during pregnancy to ensure the safety of both the mother and the developing fetus throughout the gestational period.
Medical Advice
This medication usually does not affect your ability to drive. However, if you experience hypoglycemia (low blood sugar) due to diet or other factors, you may feel dizzy or shaky. Always carry a source of fast-acting glucose and ensure your blood sugar is stable before driving or operating machinery.
Exercise Caution
Use with caution in patients with liver impairment. While metformin is not metabolized by the liver, patients with severe hepatic disease are at a higher risk of developing lactic acidosis. Regular monitoring of liver function is recommended to ensure the medication remains safe for your specific health condition.
Regular Checkup
Use with caution while breastfeeding. It is not fully known if sitagliptin or metformin passes into breast milk in significant amounts. Consult your doctor to weigh the benefits of treatment against potential risks to the nursing infant, and monitor the baby for any signs of unusual blood sugar changes.
Consult Doctor
Patients with moderate to severe kidney impairment should not use this medication. Metformin is cleared by the kidneys, and reduced function increases the risk of lactic acidosis. Consult your doctor for a thorough renal assessment and alternative treatment options if your kidney function is compromised or declining over time.
Regular Checkup
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