
Glimepiride (4mg) + Metformin (1000mg)
Active composition
+1 more active ingredient
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Metride DS 4 Tablet PR is a combination oral antidiabetic medication containing Glimepiride 4 mg and Metformin 1000 mg, indicated for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea class agent, functions by stimulating pancreatic beta cells to increase insulin secretion, thereby improving glycemic control. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and enhancing peripheral glucose uptake and utilization, contributing to improved insulin sensitivity. The synergistic action of these two agents helps achieve better blood glucose regulation compared to monotherapy. Metride DS 4 Tablet PR is typically prescribed when diet, exercise, and monotherapy with either agent fail to provide adequate glycemic control. It is essential to monitor blood glucose levels regularly and adjust the dosage based on therapeutic response and tolerability. Common side effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and hypoglycemia, particularly due to Glimepiride. Caution is advised in patients with renal or hepatic impairment, and it is contraindicated in cases of diabetic ketoacidosis or severe renal dysfunction. Patient adherence to lifestyle modifications alongside medication is critical for optimal diabetes management with Metride DS 4 Tablet PR.
How to use Metride Tablet PR Use it as advised by your doctor or check the label for directions before use. Metride DS 4 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Metride DS 4 Tablet PR.
High Risk
Metride DS 4 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Metride DS 4 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Metride DS 4 Tablet PR may be needed. Please consult your doctor. Metride DS 4 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Metride DS 4 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Metride DS 4 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Metride DS 4 Tablet PR may be needed. Please consult your doctor. Use of Metride DS 4 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Metride DS 4 Tablet PR

Glimepiride (4mg) + Metformin (1000mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Medical applications
Metride DS 4 Tablet PR is a combination oral antidiabetic medication containing Glimepiride 4 mg and Metformin 1000 mg, indicated for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea class agent, functions by stimulating pancreatic beta cells to increase insulin secretion, thereby improving glycemic control. Metformin, a biguanide, primarily acts by decreasing hepatic glucose production and enhancing peripheral glucose uptake and utilization, contributing to improved insulin sensitivity. The synergistic action of these two agents helps achieve better blood glucose regulation compared to monotherapy. Metride DS 4 Tablet PR is typically prescribed when diet, exercise, and monotherapy with either agent fail to provide adequate glycemic control. It is essential to monitor blood glucose levels regularly and adjust the dosage based on therapeutic response and tolerability. Common side effects may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and hypoglycemia, particularly due to Glimepiride. Caution is advised in patients with renal or hepatic impairment, and it is contraindicated in cases of diabetic ketoacidosis or severe renal dysfunction. Patient adherence to lifestyle modifications alongside medication is critical for optimal diabetes management with Metride DS 4 Tablet PR.
How to use Metride Tablet PR Use it as advised by your doctor or check the label for directions before use. Metride DS 4 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Metride DS 4 Tablet PR.
High Risk
Metride DS 4 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Metride DS 4 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Metride DS 4 Tablet PR may be needed. Please consult your doctor. Metride DS 4 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Metride DS 4 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Metride DS 4 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Metride DS 4 Tablet PR may be needed. Please consult your doctor. Use of Metride DS 4 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Metride DS 4 Tablet PR













