Metfra 500mg Tablet contains Metformin hydrochloride, an oral antihyperglycemic agent used primarily in the management of type 2 diabetes mellitus. Metformin belongs to the biguanide class and acts by decreasing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization. This multifaceted mechanism helps to achieve better glycemic control without causing significant hypoglycemia when used as monotherapy. Metfra 500mg is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, particularly in overweight patients or those with insulin resistance. It may be used alone or in combination with other antidiabetic agents or insulin. The medication should be administered with meals to reduce gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal discomfort. Caution is advised in patients with renal impairment, hepatic dysfunction, or conditions predisposing to hypoxia, as these increase the risk of lactic acidosis, a rare but serious adverse effect. Regular monitoring of renal function and blood glucose levels is recommended during therapy. Metfra 500mg should be used under medical supervision, with lifestyle modifications including diet and exercise for optimal therapeutic outcomes.

Dosage & How to Use