
Metformin (500mg) + Glimepiride (2mg)
Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Medical applications
Metffil G2 Tablet PR contains a combination of Glimepiride (2mg) and Metformin (500mg), indicated for the management of type 2 diabetes mellitus, particularly in patients inadequately controlled on diet and exercise alone. Glimepiride, a sulfonylurea class agent, stimulates pancreatic beta-cell insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, primarily decreases hepatic glucose production and improves peripheral insulin sensitivity, enhancing glucose uptake and utilization. The combination therapy provides complementary mechanisms to achieve better glycemic control. Metffil G2 Tablet PR is typically prescribed as part of a comprehensive diabetes management plan, including diet modification and physical activity. It is important to monitor blood glucose levels regularly to adjust dosage and avoid hypoglycemia, a potential adverse effect associated with sulfonylureas. Metformin is generally well tolerated but may cause gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort. Rarely, lactic acidosis may occur, necessitating caution in patients with renal impairment or other contraindications. This fixed-dose combination offers improved patient compliance by reducing pill burden. Prior to initiation, renal function assessment and periodic monitoring during therapy are recommended. Metffil G2 Tablet PR should be used under medical supervision, with attention to contraindications and potential drug interactions.
How to use Metffil G Tablet PR Use it as advised by your doctor or check the label for directions before use. Metffil G2 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Metffil G2 Tablet PR.
High Risk
Metffil G2 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Metffil G2 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Metffil G2 Tablet PR may be needed. Please consult your doctor. Metffil G2 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Metffil G2 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Metffil G2 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Metffil G2 Tablet PR may be needed. Please consult your doctor. Use of Metffil G2 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Metffil G2 Tablet PR

Glimepiride (2mg) + Metformin (500mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Metformin reduces hepatic glucose production and enhances peripheral insulin sensitivity, lowering blood glucose levels.
Glimepiride stimulates insulin secretion from pancreatic beta cells and enhances insulin sensitivity in peripheral tissues, facilitating glucose uptake and lowering blood sugar levels.
Medical applications
Metffil G2 Tablet PR contains a combination of Glimepiride (2mg) and Metformin (500mg), indicated for the management of type 2 diabetes mellitus, particularly in patients inadequately controlled on diet and exercise alone. Glimepiride, a sulfonylurea class agent, stimulates pancreatic beta-cell insulin secretion, thereby reducing blood glucose levels. Metformin, a biguanide, primarily decreases hepatic glucose production and improves peripheral insulin sensitivity, enhancing glucose uptake and utilization. The combination therapy provides complementary mechanisms to achieve better glycemic control. Metffil G2 Tablet PR is typically prescribed as part of a comprehensive diabetes management plan, including diet modification and physical activity. It is important to monitor blood glucose levels regularly to adjust dosage and avoid hypoglycemia, a potential adverse effect associated with sulfonylureas. Metformin is generally well tolerated but may cause gastrointestinal disturbances such as nausea, diarrhea, and abdominal discomfort. Rarely, lactic acidosis may occur, necessitating caution in patients with renal impairment or other contraindications. This fixed-dose combination offers improved patient compliance by reducing pill burden. Prior to initiation, renal function assessment and periodic monitoring during therapy are recommended. Metffil G2 Tablet PR should be used under medical supervision, with attention to contraindications and potential drug interactions.
How to use Metffil G Tablet PR Use it as advised by your doctor or check the label for directions before use. Metffil G2 Tablet PR is to be taken with food.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Metffil G2 Tablet PR.
High Risk
Metffil G2 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Exercise Caution
Metffil G2 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Metffil G2 Tablet PR may be needed. Please consult your doctor. Metffil G2 Tablet PR is generally started with a low dose in patients with mild to moderate liver disease, and its use is not recommended in patients with severe liver disease.
Regular Checkup
Metffil G2 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Metffil G2 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Metffil G2 Tablet PR may be needed. Please consult your doctor. Use of Metffil G2 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Regular Checkup
0 reviews for Metffil G2 Tablet PR













