
Ispaghula (3.5gm) + Mebeverine (135mg)
Active composition
+1 more active ingredient
Mebeverine blocks calcium channels and muscarinic receptors, leading to relaxation of gut smooth muscle and relief from spasms.
Medical applications
Matiz-I Granules is a combination pharmaceutical formulation containing Mebeverine 135 mg and Ispaghula 3.5 gm, indicated for the symptomatic relief of irritable bowel syndrome (IBS) and other functional gastrointestinal disorders characterized by abdominal pain, bloating, and altered bowel habits. Mebeverine is an antispasmodic agent that acts directly on the smooth muscle of the gastrointestinal tract, alleviating muscle spasms without affecting normal gut motility, thereby reducing abdominal cramps and discomfort. Ispaghula, a bulk-forming laxative derived from the husk of Plantago ovata seeds, functions by absorbing water in the intestines, increasing stool bulk and promoting regular bowel movements, which aids in managing constipation and maintaining bowel health. The granule formulation allows for easy oral administration, typically dissolved in water before ingestion, facilitating patient compliance. Matiz-I Granules is generally well tolerated, with minimal adverse effects; however, patients should be advised to maintain adequate hydration when using Ispaghula to prevent potential intestinal obstruction. This combination therapy offers a dual mechanism approach targeting both smooth muscle spasm and bowel regulation, making it an effective option for comprehensive management of IBS symptoms. Use should be guided by a healthcare professional based on individual patient needs and clinical response.
How to use Matiz-I Granules Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Matiz-I Granules is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol with Matiz-I Granules does not cause any harmful side effects.
High Risk
Matiz-I Granules is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Matiz-I Granules does not usually affect your ability to drive.
Exercise Caution
Matiz-I Granules is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Matiz-I Granules may not be needed in these patients. Please consult your doctor.
Regular Checkup
Information regarding the use of Matiz-I Granules during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Matiz-I Granules is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Matiz-I Granules may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Matiz-I Granules

Mebeverine (135mg) + Ispaghula (3.5gm)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Mebeverine blocks calcium channels and muscarinic receptors, leading to relaxation of gut smooth muscle and relief from spasms.
Medical applications
Matiz-I Granules is a combination pharmaceutical formulation containing Mebeverine 135 mg and Ispaghula 3.5 gm, indicated for the symptomatic relief of irritable bowel syndrome (IBS) and other functional gastrointestinal disorders characterized by abdominal pain, bloating, and altered bowel habits. Mebeverine is an antispasmodic agent that acts directly on the smooth muscle of the gastrointestinal tract, alleviating muscle spasms without affecting normal gut motility, thereby reducing abdominal cramps and discomfort. Ispaghula, a bulk-forming laxative derived from the husk of Plantago ovata seeds, functions by absorbing water in the intestines, increasing stool bulk and promoting regular bowel movements, which aids in managing constipation and maintaining bowel health. The granule formulation allows for easy oral administration, typically dissolved in water before ingestion, facilitating patient compliance. Matiz-I Granules is generally well tolerated, with minimal adverse effects; however, patients should be advised to maintain adequate hydration when using Ispaghula to prevent potential intestinal obstruction. This combination therapy offers a dual mechanism approach targeting both smooth muscle spasm and bowel regulation, making it an effective option for comprehensive management of IBS symptoms. Use should be guided by a healthcare professional based on individual patient needs and clinical response.
How to use Matiz-I Granules Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Matiz-I Granules is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Consuming alcohol with Matiz-I Granules does not cause any harmful side effects.
High Risk
Matiz-I Granules is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Matiz-I Granules does not usually affect your ability to drive.
Exercise Caution
Matiz-I Granules is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Matiz-I Granules may not be needed in these patients. Please consult your doctor.
Regular Checkup
Information regarding the use of Matiz-I Granules during breastfeeding is not available. Please consult your doctor.
Consult Doctor
Matiz-I Granules is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Matiz-I Granules may not be needed in these patients. Please consult your doctor.
Regular Checkup
0 reviews for Matiz-I Granules















