Macsita 100mg Tablet
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Sitagliptin (100mg)
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Sitagliptin inhibits DPP-4, increasing incretin levels, which stimulate insulin release and reduce glucagon secretion.
Medical applications
Macsita 100mg Tablet contains Sitagliptin, a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor indicated for the management of type 2 diabetes mellitus. Sitagliptin works by enhancing the levels of incretin hormones, which increase insulin synthesis and release from pancreatic beta cells and decrease glucagon secretion from alpha cells, thereby improving glycemic control.
Macsita is prescribed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, either as monotherapy or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin. The recommended dose is 100 mg once daily, with dose adjustments necessary in patients with renal impairment. Sitagliptin is generally well tolerated, with a low risk of hypoglycemia when used alone.
Common adverse effects may include nasopharyngitis, headache, and upper respiratory tract infections. Macsita should be used cautiously in patients with a history of pancreatitis, and therapy should be discontinued if pancreatitis is suspected. Regular monitoring of blood glucose levels and renal function is advised during treatment. Macsita 100mg Tablet offers an effective oral therapeutic option for improving glycemic control in type 2 diabetes patients.
Pyrazine-derivative
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Information regarding the use of Macsita 100mg Tablet during pregnancy is not available. Please consult your doctor.
High Risk
Macsita 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Macsita 100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Macsita 100mg Tablet may be needed. Please consult your doctor.
Exercise Caution
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Consult Doctor
Macsita 100mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Macsita 100mg Tablet may not be needed in these patients. Please consult your doctor. However, Macsita 100mg Tablet has not been studied in patients with severe hepatic impairment and is not recommended for use in such patients.
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