
Naproxen (250mg) + Domperidone (10mg)
Active composition
+1 more active ingredient
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Macprox DP 250 Tablet is a combination medication containing Naproxen 250 mg and Domperidone 10 mg, formulated to provide effective relief from pain and associated gastrointestinal discomfort. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effect by inhibiting cyclooxygenase enzymes, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever. This makes Macprox DP 250 suitable for managing conditions such as musculoskeletal pain, arthritis, and dysmenorrhea. Domperidone, a dopamine D2 receptor antagonist, enhances gastrointestinal motility and acts as an antiemetic, preventing nausea and vomiting that may occur as side effects of NSAID therapy or underlying conditions. The combination ensures improved patient compliance by addressing both pain and gastrointestinal symptoms simultaneously. Macprox DP 250 should be used under medical supervision, with caution advised in patients with a history of gastrointestinal ulcers, bleeding disorders, cardiac conditions, or hypersensitivity to either component. It is contraindicated in patients with known hypersensitivity to NSAIDs or domperidone, and in those with prolactin-releasing pituitary tumors. Common adverse effects may include gastrointestinal discomfort, headache, dizziness, and rarely, cardiac arrhythmias. Patients are advised to adhere to prescribed dosages and report any unusual symptoms promptly.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Macprox DP 250 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Macprox DP 250 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Macprox DP 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Macprox DP 250 Tablet may be needed. Please consult your doctor.
Exercise Caution
Macprox DP 250 Tablet may cause side effects which could affect your ability to drive. Macprox DP 250 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Macprox DP 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Macprox DP 250 Tablet may be needed. Please consult your doctor. Use of Macprox DP 250 Tablet is not recommended in patients with moderate and severe liver disease.
Regular Checkup
0 reviews for Macprox DP 250 Tablet

Naproxen (250mg) + Domperidone (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Naproxen inhibits COX-1 and COX-2 enzymes, decreasing the production of inflammatory mediators.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Macprox DP 250 Tablet is a combination medication containing Naproxen 250 mg and Domperidone 10 mg, formulated to provide effective relief from pain and associated gastrointestinal discomfort. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effect by inhibiting cyclooxygenase enzymes, thereby reducing the synthesis of prostaglandins responsible for inflammation, pain, and fever. This makes Macprox DP 250 suitable for managing conditions such as musculoskeletal pain, arthritis, and dysmenorrhea. Domperidone, a dopamine D2 receptor antagonist, enhances gastrointestinal motility and acts as an antiemetic, preventing nausea and vomiting that may occur as side effects of NSAID therapy or underlying conditions. The combination ensures improved patient compliance by addressing both pain and gastrointestinal symptoms simultaneously. Macprox DP 250 should be used under medical supervision, with caution advised in patients with a history of gastrointestinal ulcers, bleeding disorders, cardiac conditions, or hypersensitivity to either component. It is contraindicated in patients with known hypersensitivity to NSAIDs or domperidone, and in those with prolactin-releasing pituitary tumors. Common adverse effects may include gastrointestinal discomfort, headache, dizziness, and rarely, cardiac arrhythmias. Patients are advised to adhere to prescribed dosages and report any unusual symptoms promptly.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Macprox DP 250 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Macprox DP 250 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Macprox DP 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Macprox DP 250 Tablet may be needed. Please consult your doctor.
Exercise Caution
Macprox DP 250 Tablet may cause side effects which could affect your ability to drive. Macprox DP 250 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Consult Doctor
Macprox DP 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Macprox DP 250 Tablet may be needed. Please consult your doctor. Use of Macprox DP 250 Tablet is not recommended in patients with moderate and severe liver disease.
Regular Checkup
0 reviews for Macprox DP 250 Tablet















