Macpril H 5 Tablet
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Strip of 10 tablets • TabletPrescription requiredSchedule H
Macpril H 5 Tablet
Ramipril (5mg) + Hydrochlorothiazide (12.5mg)
₹158.80
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Ramipril 5 mg
+1 more active ingredient
How It Works
Ramipril inhibits the ACE enzyme, preventing the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure.
Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, leading to increased urine output and decreased blood volume.
Medicine Strength
5 mg
All Active Ingredients
Ramipril5 mg
Hydrochlorothiazide12.5 mg
Uses & Benefits
Medical applications
CoughBlood PressureHeart
Macpril H 5 Tablet is a combination antihypertensive medication containing Ramipril 5 mg and Hydrochlorothiazide 12.5 mg. Ramipril, an angiotensin-converting enzyme (ACE) inhibitor, works by inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation, reduced blood pressure, and decreased workload on the heart. Hydrochlorothiazide, a thiazide diuretic, promotes the excretion of sodium and water by inhibiting sodium reabsorption in the distal renal tubules, thereby reducing blood volume and contributing to blood pressure reduction.
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This combination is indicated for the management of hypertension, especially in patients who require multiple mechanisms to achieve adequate blood pressure control. Macpril H 5 Tablet may also be beneficial in reducing the risk of cardiovascular events such as stroke, myocardial infarction, and heart failure in hypertensive patients. It is important to monitor renal function, electrolytes, and blood pressure regularly during therapy due to potential side effects such as hyperkalemia, hypotension, and electrolyte imbalances.
Contraindications include hypersensitivity to ACE inhibitors or thiazides, pregnancy, and severe renal impairment. Patients should be advised to maintain adequate hydration and report any signs of angioedema or persistent cough promptly. Macpril H 5 offers a synergistic approach to hypertension management, improving patient compliance through combination therapy.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Macpril H 5 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Pregnancy
Macpril H 5 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Medical Advice
Driving
Macpril H 5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Macpril H 5 Tablet may be needed. Please consult your doctor. Regular monitoring of blood pressure is recommended for dose adjustment.
Exercise Caution
Breastfeeding
Macpril H 5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Kidney
Macpril H 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Macpril H 5 Tablet may be needed. Please consult your doctor.
Regular Checkup
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