
Metaxalone (400mg) + Diclofenac (50mg)
Active composition
+1 more active ingredient
Metaxalone depresses the central nervous system, leading to muscle relaxation and reduced muscle spasms.
Diclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Medical applications
Lysoflam-MR Tablet is a combination medication containing Diclofenac 50 mg and Metaxalone 400 mg, formulated for the effective management of musculoskeletal pain and inflammation. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain, inflammation, and swelling. Metaxalone is a centrally acting skeletal muscle relaxant that alleviates muscle spasms by depressing the central nervous system, facilitating improved mobility and comfort. Lysoflam-MR is indicated for the treatment of acute musculoskeletal conditions such as strains, sprains, and back pain, where both inflammation and muscle spasm are present. The combination provides synergistic relief, addressing both pain and muscle stiffness. It is recommended to be used under medical supervision, with caution in patients with a history of gastrointestinal ulcers, hepatic or renal impairment, and cardiovascular disorders. Common adverse effects may include gastrointestinal discomfort, dizziness, and drowsiness. Patients should avoid alcohol and activities requiring mental alertness while on this medication. Dosage and duration should be as prescribed by a healthcare professional to minimize risks and optimize therapeutic outcomes.
How to use Lysoflam-MR Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lysoflam-MR Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lysoflam-MR Tablet.
High Risk
Lysoflam-MR Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Lysoflam-MR Tablet should be used with caution in patients with liver disease. Dose adjustment of Lysoflam-MR Tablet may be needed. Please consult your doctor. Regular monitoring of liver function tests is recommended in patients with liver disease if this medicine is to be taken for a long time.
Regular Checkup
Lysoflam-MR Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Lysoflam-MR Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lysoflam-MR Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lysoflam-MR Tablet

Diclofenac (50mg) + Metaxalone (400mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Metaxalone depresses the central nervous system, leading to muscle relaxation and reduced muscle spasms.
Diclofenac inhibits COX-1 and COX-2 enzymes, leading to decreased synthesis of prostaglandins, which mediate pain and inflammation.
Medical applications
Lysoflam-MR Tablet is a combination medication containing Diclofenac 50 mg and Metaxalone 400 mg, formulated for the effective management of musculoskeletal pain and inflammation. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), exerts its therapeutic effect by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain, inflammation, and swelling. Metaxalone is a centrally acting skeletal muscle relaxant that alleviates muscle spasms by depressing the central nervous system, facilitating improved mobility and comfort. Lysoflam-MR is indicated for the treatment of acute musculoskeletal conditions such as strains, sprains, and back pain, where both inflammation and muscle spasm are present. The combination provides synergistic relief, addressing both pain and muscle stiffness. It is recommended to be used under medical supervision, with caution in patients with a history of gastrointestinal ulcers, hepatic or renal impairment, and cardiovascular disorders. Common adverse effects may include gastrointestinal discomfort, dizziness, and drowsiness. Patients should avoid alcohol and activities requiring mental alertness while on this medication. Dosage and duration should be as prescribed by a healthcare professional to minimize risks and optimize therapeutic outcomes.
How to use Lysoflam-MR Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lysoflam-MR Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Lysoflam-MR Tablet.
High Risk
Lysoflam-MR Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Lysoflam-MR Tablet should be used with caution in patients with liver disease. Dose adjustment of Lysoflam-MR Tablet may be needed. Please consult your doctor. Regular monitoring of liver function tests is recommended in patients with liver disease if this medicine is to be taken for a long time.
Regular Checkup
Lysoflam-MR Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consult Doctor
Lysoflam-MR Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lysoflam-MR Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Lysoflam-MR Tablet











